Protection from vascular risk in diabetic hypertension

被引：18

作者：

Corry D.B. ^{[1
]}

Tuck M.L. ^{[2
]}

机构：

[1] Division of Nephrology, Olive View UCLA Medical Center, Sylmar, CA 91342

[2] Division of Endocrinology, Veterans Affairs Greater Los Angeles Clinics, Sepulveda

来源：

Current Hypertension Reports | 2000年 / 2卷 / 2期

关键词：

Diabetic Nephropathy; Diabetic Retinopathy; Lisinopril; Renin Angiotensin System; Human Mesangial Cell;

D O I：

10.1007/s11906-000-0075-2

中图分类号：

学科分类号：

摘要：

Diabetes mellitus is a metabolic disorder characterized by hyperglycemia and associated with a high incidence of complications affecting both the microvascular and the macrovascular systems. Macrovascular disease affects the coronary arteries, the cerebral vessels, and the large peripheral arteries of the lower extremities. Microangiopathy affects the kidneys, eyes, and nerves. Both forms of complication are major causes of death and disability in diabetes. The precise pathophysiology of these vascular complications is becoming better understood, but specific treatment and prevention remain complex. Copyright © 2000 by Current Science Inc.

引用

页码：154 / 159

页数：5

共 41 条

[21]

Danser A.H., Derkx F.H., Admiraal P.J., Et al., Angiotensin levels in the eye, Invest Ophthalmol Vis Sci, 35, pp. 1008-1018, (1994)

[22]

Wagner J., Jan Danser A.H., Derkx F.H., Et al., Demonstration of renin mRNA, angiotensinogen mRNA and angiotensin converting enzyme mRNA expression in the human eye: Evidence for an intraocular renin-angiotensin system, Br J Ophthalmol, 80, pp. 159-163, (1996)

[23]

Makimattila S., Summanen P., Matinlauri I., Et al., Serum total renin: An independent marker of the activity and severity of retinopathy in patients with IDDM, Br J Ophtalmol, 82, pp. 939-944, (1998)

[24]

Chase H.P., Garg S.K., Harris S., Et al., Angiotensin-converting enzyme inhibitor treatment of young normotensive diabetic subjects: A two-year trial, Ann Ophthalmol, 25, pp. 284-289, (1993)

[25]

Larsen M., Hommel E., Parving H.H., Lund-Handersen H., Protective effect of captopril on the blood-retina barrier in normotensive insulin-dependent patients with nephropathy and background retinopathy, Graefes Arch Clin Exp Ophthalmol, 228, pp. 505-509, (1990)

[26]

Ravid M., Savin H., Jutrin I., Et al., Long-term stabilizing effect of angiotensin-converting enzyme inhibition on plasma creatinine and on proteinuria in normotensive type II diabetic patients, Ann Intern Med, 118, pp. 577-581, (1993)

[27]

Chaturvedi N., Sjolie A.K., Stephenson J.M., Et al., Effect of lisinopril on progression of retinopathy in normotensive people with type 1 diabetes, Lancet, 351, pp. 28-31, (1998)

[28]

Poulsen P.L., Bek T., Ebbehloj E., Et al., 24-h ambulatory blood pressure and retinopathy in normoalbuminuric IDDM patients, Diabetologia, 41, pp. 105-110, (1998)

[29]

The United States Renal Data System: USRDS Annual Data Report, (1995)

[30]

Nelson R.G., Bennett P.H., Beck G.J., Et al., Development and progression of diabetic nephropathy in Pima Indians with non-insulin-dependent diabetes mellitus, N Engl J Med, 335, pp. 1636-1642, (1996)

← 1 2 3 4 5 →