An international database and integrated analysis tools for the study of cancer gene expression

被引：22

作者：

Strausberg R.L. ^{[1
]}

Camargo A.A. ^{[2
]}

Riggins G.J. ^{[3
]}

Schaefer C.F. ^{[1
]}

De Souza S.J. ^{[2
]}

Grouse L.H. ^{[1
]}

Lal A. ^{[3
]}

Buetow K.H. ^{[1
]}

Boon K. ^{[3
]}

Greenhut S.F. ^{[1
]}

Simpson A.J.G. ^{[2
]}

机构：

[1] National Cancer Institute, Bethesda, MD

[2] Ludwig Institute for Cancer Research, São Paulo

[3] Duke University Medical Center, Durham, NC

来源：

The Pharmacogenomics Journal | 2002年 / 2卷 / 3期

基金：

巴西圣保罗研究基金会;

关键词：

Cancer; CGAP; Gene expression; Genomics; ORESTES; SAGE;

D O I：

10.1038/sj.tpj.6500103

中图分类号：

学科分类号：

摘要：

Researchers working collaboratively in Brazil and the United States have assembled an International Database of Cancer Gene Expression. Several strategies have been employed to generate gene expression data including expressed sequence tags (ESTs), serial analysis of gene expression (SAGE), and open reading-frame expressed sequence tags (ORESTES). The database contains six million gene tags that reflect the gene expression profiles in a wide variety of cancerous tissues and their normal counterparts. All sequences are deposited in the public databases, GenBank and SAGEmap. A suite of informatics tools was designed to facilitate in silico analysis of the gene expression datasets and are available through the NCI Cancer Genome Anatomy Project web site (http://cgap.nci.nih.gov).

引用

页码：156 / 164

页数：8

共 39 条

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