Critical illness polyneuropathy

被引：10

作者：

Bolton C.F. ^{[1
]}

Young G.B. ^{[2
]}

机构：

[1] Department of Neurology, Mayo Medical School, Mayo Clinic and Foundation, 200 First Street, SW, Rochester, 55905, MN

[2] Department of Clinical Neurological Services, University of Western Ontartio, Victoria Campus, London, N6A 4G5, ON

来源：

Current Treatment Options in Neurology | 2000年 / 2卷 / 6期

关键词：

Critical Illness; Critical Illness Polyneuropathy; Multiple Organ Failure; Myopathy; Systemic Inflammatory Response Syndrome;

D O I：

10.1007/s11940-000-0027-9

中图分类号：

学科分类号：

摘要：

Critical illness polyneuropathy (CIP) is common among patients in intensive care units (ICUs) [1, Class III]. However, it is rarely diagnosed in patients in most ICUs, because of the lack of knowledge, difficulties in clinical assessment, and failure to perform electrophysiologic studies. Nonetheless, CIP is a significant cause of difficulty in weaning patients from the ventilator and of long-term morbidity in survivors. Although no specific treatment is available, diagnosis is important for the institution of various nonspecific treatments and for prognosis. Moreover, research is important in arriving at a better understanding of the pathophysiologic mechanisms and, hence, possible avenues of specific treatment. Thus, this chapter emphasizes the nature of critical illness and the possible pathophysiology, the clinical and electrophysiologic features, and the differential diagnosis of CIP. Nonspecific and potential specific treatments are also discussed. © 2000, Current Science Inc.

引用

页码：489 / 498

页数：9

共 33 条

[1]

Bolton C.F., Critical illness polyneuropathy, Peripheral Nerve Disorders 2, pp. 262-280, (1995)

[2]

Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis, Crit Care Med, 20, pp. 864-874, (1992)

[3]

Bolton C.F., Sepsis and the systemic inflammatory response syndrome: neuromuscular manifestations, Crit Care Med, 24, pp. 1408-1416, (1996)

[4]

Young G.B., Bolton C.F., Austin T.W., Et al., The encephalopathy associated with septic illness, Clin Invest Med, 13, pp. 297-304, (1990)

[5]

Zifko U.A., Zipko H.T., Bolton C.F., Clinical and electrophysiological findings in critical illness polyneuropathy, J Neurol Sci, 159, pp. 186-193, (1998)

[6]

Zochodne D.W., Bolton C.F., Wells G.A., Et al., Critical illness polyneuropathy: a complication of sepsis and multiple organ failure, Brain, 110, pp. 819-841, (1987)

[7]

Leijten F.S., de Weerd A.W., Critical illness polyneuropathy. A review of the literature, definition and pathophysiology, Clin Neurol Neurosurg, 96, pp. 10-19, (1994)

[8]

Rich M.M., Bird S.J., Raps E.C., Et al., Direct muscle stimulation in acute quadriplegic myopathy, Muscle Nerve, 20, pp. 665-673, (1997)

[9]

Bolton C.F., AAEM minimonograph #40: clinical neurophysiology of the respiratory system, Muscle Nerve, 16, pp. 809-818, (1993)

[10]

McKhann G.M., Cornblath D.R., Griffin J.W., Et al., Acute motor axonal neuropathy: a frequent cause of acute flaccid paralysis in China, Ann Neurol, 33, pp. 333-342, (1993)

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