Critical illness polyneuropathy

被引：10

作者：

Bolton C.F. ^{[1
]}

Young G.B. ^{[2
]}

机构：

[1] Department of Neurology, Mayo Medical School, Mayo Clinic and Foundation, 200 First Street, SW, Rochester, 55905, MN

[2] Department of Clinical Neurological Services, University of Western Ontartio, Victoria Campus, London, N6A 4G5, ON

来源：

Current Treatment Options in Neurology | 2000年 / 2卷 / 6期

关键词：

Critical Illness; Critical Illness Polyneuropathy; Multiple Organ Failure; Myopathy; Systemic Inflammatory Response Syndrome;

D O I：

10.1007/s11940-000-0027-9

中图分类号：

学科分类号：

摘要：

Critical illness polyneuropathy (CIP) is common among patients in intensive care units (ICUs) [1, Class III]. However, it is rarely diagnosed in patients in most ICUs, because of the lack of knowledge, difficulties in clinical assessment, and failure to perform electrophysiologic studies. Nonetheless, CIP is a significant cause of difficulty in weaning patients from the ventilator and of long-term morbidity in survivors. Although no specific treatment is available, diagnosis is important for the institution of various nonspecific treatments and for prognosis. Moreover, research is important in arriving at a better understanding of the pathophysiologic mechanisms and, hence, possible avenues of specific treatment. Thus, this chapter emphasizes the nature of critical illness and the possible pathophysiology, the clinical and electrophysiologic features, and the differential diagnosis of CIP. Nonspecific and potential specific treatments are also discussed. © 2000, Current Science Inc.

引用

页码：489 / 498

页数：9

共 33 条

[21]

Karpati G., Carpenter S., Eisen A.A., Experimental core-like lesions and nemaline rods: a correlative morphological and physiological study, Arch Neurol, 27, pp. 237-251, (1972)

[22]

Op de Coul A.A., Verheul G.A., Leyten A.C., Et al., Critical illness polyneuromyopathy after artificial respiration, Clin Neurol Neurosurg, 93, pp. 27-33, (1991)

[23]

Baue A.E., Berlot G., Gullo A., Sepsis and Organ Dysfunction: Epidemiology and Scoring Systems: Pathophysiology and Therapy, (1998)

[24]

Leijten F.S., Harinck-de Weerd J.E., Poortvliet D.C., de Weerd A.W., The role of polyneuropathy in motor convalescence after prolonged mechanical ventilation, JAMA, 274, pp. 1221-1225, (1995)

[25]

Opal S.M., Yu R.L., Antiendotoxin strategies for the prevention and treatment of septic shock. New approaches and future directions, Drugs, 55, pp. 497-508, (1998)

[26]

Levy H., Ash S.R., Knab W., Et al., Systemic inflammatory response syndrome treatment by powdered sorbent pheresis: the BioLogic-Detoxification Plasma Filtration System, Asaio J, 44, pp. M659-M665, (1998)

[27]

Vincent J.L., Tielemans C., Continuous hemofiltration in severe sepsis: is it beneficial?, J Crit Care, 10, pp. 27-32, (1995)

[28]

Werdan K., Supplemental immune globulins in sepsis, Clin Chem Lab Med, 37, pp. 341-349, (1999)

[29]

Mohr M., Englisch L., Roth A., Et al., Effects of early treatment with immunoglobulin on critical illness polyneuropathy following multiple organ failure and gram-negative sepsis, Intensive Care Med, 23, pp. 1144-1149, (1997)

[30]

Waldhausen E., Mingers B., Lippers P., Keser G., Critical illness polyneuropathy due to parenteral nutrition (letter), Intensive Care Med, 23, pp. 922-923, (1997)

← 1 2 3 4 →