Obesity and cardiovascular hemodynamic function

被引：19

作者：

Koch R. ^{[1
]}

Sharma A.M. ^{[1
]}

机构：

[1] Medizinische Klinik, Klinkum Benjamin Franklin, Free University of Berlin, Hindenburgdamm 30, D-12200, Berlin

来源：

Current Hypertension Reports | 1999年 / 1卷 / 2期

关键词：

Left Ventricle; Left Atrial; Atrial Natriuretic Peptide; Dexfenfluramine; Concentric Hypertrophy;

D O I：

10.1007/s11906-999-0006-9

中图分类号：

学科分类号：

摘要：

Marked abnormalities in cardiovascular structure and hemodynamic function are present both in normotensive and hypertensive obese individuals. Cardiac abnormalities include excentric left ventricular hypertrophy and left atrial dilatation, a finding compatible with the presence of cardiac volume overload. In contrast, hypertension, often associated with abdominal obesity, is characterized by increased peripheral resistance and concentric hypertrophy. Weight reduction can result in marked improvement of ventricular dimensions and cardiac function in patients undergoing massive weight reduction following bariatric surgery. In this paper we review recent findings that have broadened our understanding of cardiovascular hemodynamic function in obesity. Copyright © 1999 by Current Science Inc.

引用

页码：127 / 130

页数：3

共 23 条

[11]

Crandall, D.L., Hausman, G.J., Kral, J.G., A review of the microcirculation of adipose tissue: Anatomic, metabolic, and angiogenic perspectives (1997) Microcirculation, 4, pp. 211-232

[12]

Crandall, D.L., Gordon, G., Herzlinger, H.E., Transforming growth factor alpha and atrial natriuretic peptide in white adipose tissue depots in rats (1992) Eur J Clin Invest, 22, pp. 676-680

[13]

Frederich Jr., R.C., Kahn, B.B., Peach, M.J., Flier, J.S., Tissue-specific nutritional regulation of angiotensinogen in adipose tissue (1992) Hypertension, 19, pp. 339-344

[14]

Jones, B.H., Standridge, M.K., Taylor, J.W., Moustaid, N., Angiotensinogen gene expression in adipose tissue: Analysis of obese models and hormonal and nutritional control (1997) Am J Physiol, 273, pp. R236-R242

[15]

Daniels, S.R., Kimball, T.R., Khoury, P., Correlates of the hemodynamic determinants of blood pressure (1996) Hypertension, 28, pp. 37-41

[16]

Crandall, D.L., Di Girolamo, M., Hemodynamic and metabolic correlates in adipose tissue: Pathophysiologic considerations (1990) FASEB J, 4, pp. 141-147

[17]

Segal, K.R., Lacayanga, I., Dunaif, A., Impact of body fat mass and percent fat on metabolic rate and thermogenesis in men (1989) Am J Physiol, 256, pp. 573-579

[18]

Mureddu, G.F., De Simone, G., Greco, R., Left ventricular filling in arterial hypertension. Influence of obesity and hemodynamic and structural confounders (1997) Hypertension, 29, pp. 544-550

[19]

Jern, S., Bergbrant, A., Bjorntorp, P., Hansson, L., Relation of central hemodynamics to obesity and body fat distribution (1992) Hypertension, 19, pp. 520-527

[20]

Vetta, F., Cicconetti, P., Ronzoni, S., Hyperinsulinaemia, regional adipose tissue distribution and left ventricular mass in normotensive, elderly, obese subjects (1998) Eur Heart J, 19, pp. 326-331

← 1 2 3 →