P2Y receptors and pain transmission

被引：84

作者：

Gerevich Z. ^{[1
]}

Illes P. ^{[1
]}

机构：

[1] Rudolf-Boehm-Institute of Pharmacology and Toxicology, University of Leipzig, Leipzig 04107

来源：

Purinergic Signalling | 2004年 / 1卷 / 1期

关键词：

Analgesia; Dorsal root ganglion; Electrophysiology; Immunohistochemistry; P2Y receptor;

D O I：

10.1007/s11302-004-4740-9

中图分类号：

学科分类号：

摘要：

It is widely accepted that the most important ATP receptors involved in pain transmission belong to the P2X3 and P2X2/3 subtypes, selectively expressed in small diameter dorsal root ganglion (DRG) neurons. However, several types of the metabotropic ATP (P2Y) receptors have also been found in primary afferent neurons; P2Y1 and P2Y2 receptors are typically expressed in small, nociceptive cells. Here we review the results available on the involvement of P2Y receptors in the modulation of pain transmission. © Springer 2004.

引用

页码：3 / 10

页数：7

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