Multiple Mechanisms for Regulation of the Transcriptional Activity of Thyroid Hormone Receptors

被引:154
作者
Sheue-yann Cheng
机构
[1] National Institutes of Health,Gene Regulation Section, Laboratory of Molecular Biology, Division of Basic Sciences, National Cancer Institute
关键词
thyroid hormone; thyroid hormone receptor; transcriptional regulation; corepressor; coactivator; gene regulation;
D O I
10.1023/A:1010052101214
中图分类号
学科分类号
摘要
引用
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页码:9 / 18
页数:9
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[11]  
Appella E(1998)Recessive resistance to thyroid hormone in mice lacking thyroid hormone receptor beta: evidence for tissue-specific modulation of receptor function EMBO J 17 455-461
[12]  
Merlino GR(1997)Thyroid hormone receptor beta is essential for development of auditory function EMBO J 16 4412-4420
[13]  
Pastan I.(1999)Abnormal heart rate and body temperature in mice lacking thyroid hormone receptor alpha 1 Genes Dev 13 1329-1341
[14]  
Weinberger C(1991)The T3R alpha gene encoding a thyroid hormone receptor is essential for post-natal development and thyroid hormone production Nature 352 497-505
[15]  
Thompson CC(1995)Mice devoid of all known thyroid hormone receptors are viable but exhibit disorders of the pituitarythyroid axis, growth, and bone maturation Nature 375 203-211
[16]  
Ong ES(1993)Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA J Biol Chem 268 19392-19397
[17]  
Lebo R(1997)Structural determinants of nuclear receptor assembly on DNA direct repeats Endocrinology 138 1456-1463
[18]  
Gruol DJ(1995)Nonbiased identification of DNA sequences that bind thyroid hormone receptor alpha 1 with high affinity Mol Cell Endocrinol 107 1-12
[19]  
Evans RM.(1993)Differential sensitivity of thyroid hormone receptor isoform homodimers and mutant heterodimers to hormone-induced dissociation from DNA: Its role in dominant negative action TEM 4 156-162
[20]  
Sap J(1994)Modulation of thyroid hormone action by mutant thyroid hormone receptors, Nature 370 382-386