The role of prefrontal cortex in resolving distractor interference

被引：69

作者：

Jha A.P. ^{[1
,2
]}

Fabian S.A. ^{[1
]}

Aguirre G.K. ^{[1
]}

机构：

[1] University of Pennsylvania, Philadelphia, PA

[2] Center for Cognitive Neuroscience, University of Pennsylvania, Philadelphia, PA 19104

来源：

Cognitive, Affective, & Behavioral Neuroscience | 2004年 / 4卷 / 4期

关键词：

Congruency Effect; Work Memory Task; Blood Oxygenation Level Dependent; Delay Interval; Proactive Interference;

D O I：

10.3758/CABN.4.4.517

中图分类号：

学科分类号：

摘要：

We investigate the hypothesis that those subregions of the prefrontal cortex (PFC) found to support proactive interference resolution may also support delay-spanning distractor interference resolution. Ten subjects performed delayed-recognition tasks requiring working memory for faces or shoes during functional MRI scanning. During the 15-sec delay interval, task-irrelevant distractors were presented. These distractors were either all faces or all shoes and were thus either congruent or incongruent with the domain of items in the working memory task. Delayed-recognition performance was slower and less accurate during congruent than during incongruent trials. Our fMRI analyses revealed significant delay interval activity for face and shoe working memory tasks within both dorsal and ventral PFC. However, only ventral PFC activity was modulated by distractor category, with greater activity for congruent than for incongruent trials. Importantly, this congruency effect was only present for correct trials. In addition to PFC, activity within the fusiform face area was investigated. During face distraction, activity was greater for face relative to shoe working memory. As in ventrolateral PFC, this congruency effect was only present for correct trials. These results suggest that the ventrolateral PFC and fusiform face area may work together to support delay-spanning interference resolution. Copyright 2004 Psychonomic Society, Inc.

引用

页码：517 / 527

页数：10

共 69 条

[41]

Malmo R., Interference factors in delayed response in monkeys after removal of frontal lobes, Journal of Neurophysiology, 5, pp. 295-308, (1942)

[42]

Mangun G.R., Buonocore M.H., Girelli M., Jha A.P., ERP and f MRI measures of visual spatial selective attention, Human Brain Mapping, 6, pp. 383-389, (1998)

[43]

Marcer D., Interference and short-term retention, British Journal of Psychology, 63, pp. 533-536, (1972)

[44]

May C.P., Hasher L., Kane M.J., The role of interference in memory span, Memory & Cognition, 27, pp. 759-767, (1999)

[45]

McCarthy G., Puce A., Gore J.C., Allison T., Face-specific processing in the human fusiform gyrus, Journal of Cognitive Neuroscience, 9, pp. 605-610, (1997)

[46]

McIntyre J.S., Stojak R.A., Mostoway W., Individual organization and release from proactive interference, Journal of Experimental Psychology, 98, pp. 164-168, (1973)

[47]

Milham M.P., Banich M.T., Webb A., Barad V., Cohen N.J., Wszalek T., Kramer A.F., The relative involvement of anterior cingulate and prefrontal cortex in attentional control depends on nature of conflict, Cognitive Brain Research, 12, pp. 467-473, (2001)

[48]

Miller E.K., Cohen J.D., An integrative theory of prefrontal cortex function, Annual Review of Neuroscience, 24, pp. 167-202, (2001)

[49]

Miller E.K., Erickson C.A., Desimone R., Neural mechanisms of visual working memory in prefrontal cortex of the macaque, Journal of Neuroscience, 16, pp. 5154-5167, (1996)

[50]

Miller E.K., Li L., Desimone R., A neural mechanism for working and recognition memory in inferior temporal cortex, Science, 254, pp. 1377-1379, (1991)

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