Fumonisin intake of the German consumer

被引：25

作者：

Zimmer I. ^{[1
,2
]}

Usleber E. ^{[3
]}

Klaffke H. ^{[4
]}

Weber R. ^{[4
]}

Majerus P. ^{[5
]}

Otteneder H. ^{[5
]}

Gareis M. ^{[6
]}

Dietrich R. ^{[1
]}

Märtlbauer E. ^{[1
]}

机构：

[1] Chair of Hygiene and Technology of Milk, Department of Veterinary Sciences, Ludwig-Maximilians-University of Munich, 85764 Oberschleissheim

[2] Central Science Laboratory, Veterinary Surveillance Team

[3] Institute of Veterinary Food Science, Veterinary Faculty, Justus-Liebig-University, 35390 Giessen

[4] Bundesinstitut für Risikobewertung, 14195 Berlin

[5] Landesuntersuchungsamt-Institut für Lebensmittelchemie, 54295 Trier

[6] Institute of Microbiology and Biotechnology, Max Rubner-Institute, 95326 Kulmbach

来源：

Mycotoxin Research | 2008年 / 24卷 / 1期

关键词：

Diet; Food; Fumonisin; Infant; Maize; Mycotoxin;

D O I：

10.1007/BF02985269

中图分类号：

学科分类号：

摘要：

In order to calculate the dietary fumonisin intake of the German consumer, a large survey was carried out on a variety of potentially contaminated products in the period between December 1998 and July 2001. A total of 1960 food samples comprising all known relevant groups of products were analysed for fumonisins. Furthermore, 272 of these samples were also analysed for hydrolysed fumonisins (HFB). For routine analysis enzyme immunoassay was used, confirmatory and control analyses were performed using HPLC-FLD after precolumn derivatisation, or by LC-MS/MS. Daily intake of fumonisins was calculated by combining fumonisin contamination data obtained in this study with available food consumption data for Germany. In a "mean case" scenario, median fumonisin levels in foods and mean food intake values were used. To generate a "bad case" scenario, the 90th percentile of fumonisin levels in foods and mean food intake values were combined. The overall daily fumonisin intake by the German consumer was 1.1 μg in the "mean case" scenario, and 21 μg in the "bad case" scenario. It was concluded that in general there is no increased risk for the German consumer in aspects of exceeding the recommended tolerable daily intake of fumonisins (2 μg/kg body weight). However, certain products (and certain brands of products) were repeatedly found to contain elevated fumonisin levels, which in a "worst case" scenario ("high" food intake of maize-based products) could pose a potential risk for the consumer, in particular concerning foods for infants and young children. High fumonisin levels were found in infant foods in 1999, but contamination levels decreased strongly in the following years. HFBs (mostly HFB1) were frequently found in processed cereals such as corn flakes, but in relatively low concentrations. According to our findings, the new European Union maximum levels for fumonisins are suitable to eliminate peak contamination levels of fumonisins in foods, but would lead to a regular excess of the TDI for infants and young children if these maximum levels would indeed be exhausted. © 2008 Springer.

引用

页码：40 / 52

页数：12

共 78 条

[21]

Oesophageal and other main cancer patterns in four districts of Transkei, 1981-1984, South African Medical Journal, 72, 1, pp. 27-30, (1987)

[22]

Franceschi S., Bidoli E., Baron A.E., La Vecchia C., Maize and risk of cancers of the oral cavity, pharynx, and esophagus in Northeastern Italy, Journal of the National Cancer Institute, 82, 17, pp. 1407-1411, (1990)

[23]

Sydenham E.W., Gelderblom W.C.A., Thiel P.G., Marasas W.F.O., Natural occurrence of someFusarium mycotoxins in corn from low and high oesophageal cancer prevalence areas of the Transkei, Southern Africa, J Agric Food Chem, 38, pp. 1900-1903, (1990)

[24]

Rheeder J.P., Marasas W.F.O., Thiel P.G., Sydenham E.W., Shepard G.S., Van Schalkwyk D.J., Fusarium moniliforme and fumonisins in corn in relation to human esophageal cancer in Transkei, Phytopathology, 82, pp. 353-357, (1992)

[25]

Chu F.S., Li G.Y., Simultaneous occurrence of fumonisin B<sub>1</sub> and other mycotoxins in moldy corn collected from the People's Republic of China in regions with high incidences of esophageal cancer, Applied and Environmental Microbiology, 60, 3, pp. 847-852, (1994)

[26]

Yoshizawa T., Yamashita A., Luo Y., Fumonisin occurrence in corn from high- and low-risk areas for human esophageal cancer in China, Applied and Environmental Microbiology, 60, 5, pp. 1626-1629, (1994)

[27]

Gao H.P., Yoshizawa T., Further study onFusarium mycotoxins in corn and wheat from a high-risk area for human esophageal cancer in China, Mycotoxins, 45, pp. 51-55, (1997)

[28]

Zhang H., Nagashima H., Goto T., Natural occurrence of mycotoxins in corn, samples from high and low risk areas for human esophageal cancer in China, Mycotoxins, 44, pp. 29-35, (1997)

[29]

Shephard G.S., Marasas W.F.O., Burger H.-M., Somdyala N.I.M., Rheeder J.P., Van Der Westhuizen L., Gatyeni P., Van Schalkwyk D.J., Exposure assessment for fumonisins in the former Transkei region of South Africa, Food Additives and Contaminants, 24, 6, pp. 621-629, (2007)

[30]

IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. Volume 56 Some Naturally Occurring Substances: Food Items and Constituents, Heterocyclic Aromatic Amines and Mycotoxins, (1993)

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