Adiponectin: Protection of the endothelium

被引：74

作者：

Lam K.S.L. ^{[1
]}

Xu A. ^{[1
]}

机构：

[1] Department of Medicine, Research Centre of Heart, Brain, Hormone and Healthy Aging, University of Hong Kong, Pokfulam

来源：

Current Diabetes Reports | 2005年 / 5卷 / 4期

关键词：

Adiponectin Level; Serum Adiponectin; Arterioscler Thromb Vasc Biol; High Molecular Weight Adiponectin; High Molecular Weight Form;

D O I：

10.1007/s11892-005-0019-y

中图分类号：

学科分类号：

摘要：

Low levels of adiponectin, a fat-derived hormone, are found in coronary heart disease, type 2 diabetes, obesity, and other insulin-resistant states. Conversely, high adiponectin levels are predictive of reduced coronary risk in long-term epidemiologic studies. A close association between hypoadiponectinemia and endothelial dysfunction has also been demonstrated. The various mechanisms through which adiponectin may protect the endothelium, via its insulin-sensitizing, antiatherogenic, anti-inflammatory, and antioxidant properties, are reviewed. Copyright © 2005 by Current Science Inc.

引用

页码：254 / 259

页数：5

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