Phantom limb pain.

被引：2

作者：

Nikolajsen L. ^{[1
]}

Staehelin Jensen T. ^{[1
]}

机构：

[1] Department of Neurology and Danish Pain Research Center, University of Aarhus, Aarhus Kommunehospital, Building 1 C, Aarhus C, Nørrebrogade 44

来源：

Current Review of Pain | 2000年 / 4卷 / 2期

关键词：

Memantine; Transcutaneous Electrical Nerve Stimulation; Phantom Limb; Phantom Limb Pain; Cortical Reorganization;

D O I：

10.1007/s11916-000-0052-0

中图分类号：

学科分类号：

摘要：

Phantom pain is experienced by 60% to 80% of patients following limb amputation but is only severe in about 5% to 10% of cases. The mechanisms underlying pain in amputees are not fully understood, but factors in both the peripheral and central nervous system play a role. Treatment of phantom pain is not successful; a recent study on prevention of phantom pain showed negative results. The future may reveal new specific drugs for treatment.

引用

页码：166 / 170

页数：4

共 87 条

[11]

Krebs B(1997)The relationship of phantom limb pain to other phantom limb phenomena in upper extremity amputees Pain 72 87-93

[12]

Nielsen J(1990)Pain memories in phantom limbs: review and clinical observations Pain 43 319-336

[13]

Sherman RA(1996)Pain memories in phantom limbs: a case study Pain 66 381-384

[14]

Sherman CJ(1997)Peripheral and central hyperexcitability: differential signs and symptoms in persistent pain Behav Brain Sci 20 404-419

[15]

Wilkins KL(1991)The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states Pain 44 293-299

[16]

McGrath PJ(1992)Peripheral nerve injury triggers central sprouting of myelinated afferents Nature 355 75-78

[17]

Finley GA(1995)Phantom limb pain as a perceptual correlate of massive cortical reorganization in upper limb amputees Nature 375 482-484

[18]

Flor H(1996)Evidence for a change in neural processing in phantom limb pain patients Pain 67 275-283

[19]

Elbert T(1997)Effects of regional anaesthesia on phantom limb pain are mirrored in changes in cortical reorganization J Neurosci 17 5503-5508

[20]

Muhlnickel W(1992)Calcitonin in phantom limb pain: a double-blind study Pain 48 21-27

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