A comparison of gestational days gained with oral terbutaline versus continuous subcutaneous terbutaline in women with twin gestations

被引:9
作者
Lam F. [1 ]
Bergauer N.K. [2 ]
Coleman S.K. [2 ]
Stanziano G.J. [2 ]
Jacques D. [2 ]
机构
[1] California Pacific Medical Center, San Francisco, CA
[2] Matria Healthcarem Inc., Marietta, GA
关键词
D O I
10.1038/sj.jp.7200424
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学科分类号
摘要
OBJECTIVE: To compare gestational days gained with oral versus subcutaneous terbutaline for maintenance tocolysis. STUDY DESIGN: In retrospective fashion 386 women enrolled in an outpatient preterm labor identification program met the following criteria: twin gestation, development of threatened preterm labor resulting in treatment with oral terbutaline, and subsequent recurrence of threatened preterm labor resulting in treatment with continuous subcutaneous terbutaline. The primary outcome was gestational days gained with oral terbutaline versus gain with continuous subcutaneous terbutaline. RESULTS: There were significantly more days gained during subcutaneous treatment than during oral treatment (34.0±19.8 versus 19.3±15.3 days). Thirty-three percent of desired prolongation was achieved with oral terbutaline, whereas 79% of desired prolongation was achieved with subcutaneous terbutaline (p<0.001). Patients gained a mean of 53.4±21.4 days overall with outpatient tocolysis. The mean gestational age at delivery was 35.2±1.9 weeks. CONCLUSION: Continuous subcutaneous terbutaline was superior to oral terbutaline in prolonging gestation in women with twin gestations. © 2000 Nature America Inc.
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页码:408 / 413
页数:5
相关论文
共 27 条
[21]  
Katz M., Newman R.B., Gill P.J., Assessment of uterine activity in ambulatory patients at risk for preterm labor and delivery, Am J Obstet Gynecol, 154, pp. 44-47, (1986)
[22]  
Garite T.J., Bentley D.L., Hamer C.A., Porto M.L., Uterine activity characteristics in multiple gestations, Obstet Gynecol, 76, pp. 56S-59S, (1990)
[23]  
Lam F., Bergauer N.K., Stanziano G.J., Jacques D., Pregnancy prolongation and route of tocolytic administration inpatients with singleton gestation, Am J Obstet Gynecol, 178, (1998)
[24]  
Allbert J.R., Johnson C., Roberts W.E., Et al., Tocolysis for recurrent preterm labor using a continuous subcutaneous infusion pump, J Reprod Med, 39, pp. 614-618, (1994)
[25]  
Elliott J.P., Flynn M.J., Kaemmerer E.L., Radin T.G., Terbutaline pump tocolysis in high-order multiple gestation, J Reprod Med, 42, pp. 687-694, (1997)
[26]  
Moise K.J., Sala D.J., Zurawin R.K., Cano L.E., Hesketh D.E., Carpenter R.J., Continuous subcutaneous terbutaline pump for premature labor: Safety and efficacy, South Med J, 85, pp. 255-260, (1992)
[27]  
Moore T.R., Lams J.D., Creasy R.K., Burau K.D., Davidson A.L., Diurnal and gestational patterns of uterine activity in normal human pregnancy, Obstet Gynecol, 83, pp. 517-523, (1994)