Flavonols, flavones and anthocyanins as native antioxidants of food and their possible role in the prevention of chronic diseases [Flavonole, flavone und anthocyane als naturliche antioxidantien der nahrung und ihre mogliche rolle bei der pravention chronischer erkrankungen]

被引:105
作者
Böhm H. [1 ]
Boeing H. [1 ]
Hempel J. [1 ]
Raab B. [1 ]
Kroke A. [1 ]
机构
[1] Deutsches Institut für Ernährungsforschung,
[2] Arthur-Schenuert-Allee 114–116,undefined
[3] D-14558 Bergholz-Rehbrücke,undefined
关键词
Anthocyanins; Antioxidative effects; Bioavailability; Flavones; Flavonoids; Flavonols; Prevention;
D O I
10.1007/PL00007376
中图分类号
学科分类号
摘要
Flavonoids are non-nutritive compounds of plants that have been intensively investigated during the past years due to their possible protective effects against chronic diseases. In vitro studies were able to demonstrate for flavonols, flavones, and most recently also for anthocyanins a considerable antioxidative activity, mainly based on scavenging of oxygen radicals. Flavonols and anthocyanins are commonly found in European fruits and vegetables. In addition, black tea and red wine may have a high content of these compounds. Those food items are the main sources of flavonol consumption each contributing to a different degree to the overall intake. The absorption of aglycones has been established before. However, only recently could the absorption of flavonolglycosides be demonstrated. The mean intake of flavonols of the German population was calculated using data from the National German Food Consumption Survey. According to this analysis, the daily per capita intake was about 11.5 mg flavonols, mainly derived from fruits and vegetables, but also from black tea and red wine. Epidemiological studies have been directed to investigate the association between flavonol consumption and disease risk. An inverse association between flavonol intake and mortality from myocardial infarction was observed. According to one of three studies, the flavonoid intake can be inversely correlated with cancer risk. This review summarizes the current knowledge on the occurrence, intake, bioavailability, and antioxidative properties of flavonols, flavones, and anthocyanins as well as the associations between flavonol intake and disease risks. Possible health related effects especially of flavonols are critically reflected, and the necessity of further research is outlined.
引用
收藏
页码:147 / 163
页数:16
相关论文
共 144 条
  • [1] Van Acker S.A., Van Den B.D., Tromp M.N., Griffioen D.H., Van Bennekom W.P., Van Der V.W., Bast A., Structural Aspects of Antioxidant Activity of Flavonoids, Free Radical Biol Med, 20, pp. 331-342, (1996)
  • [2] Van A.S., Tromp M., Haenen G., Van Der V.W., Bast A., Flavonoids as Scavengers of Nitric Oxide Radical, Biochem Biophys Res Comm, 214, pp. 755-759, (1995)
  • [3] Adolf T.H., Public Use File, Nationale Verzehrsstudie (NVS) und Verbundstudie Ernährungserhebung und Risikofaktorenanalytik (VERA), (1991)
  • [4] Afanas'ev I.B., Dorozhko A.I., Brodskii A.V., Kostyuk V.A., Potapovitch A.I., Chelating and Free Radical Scavenging Mechanisms of Inhibitory Action of Rutin and Quercetin in Lipid Peroxidation, Biochem Pharmacol, 38, pp. 1763-1769, (1989)
  • [5] Ames B.N., Dietary Carcinogens and Anticarcinogens, Science, 221, pp. 1256-1264, (1983)
  • [6] Aruoma O.I., Nutrition and Health Aspects of Free Radicals and Antioxidants, Fd Chem Toxic, 32, pp. 671-683, (1994)
  • [7] Balentine D.A., Manufacturing and Chemistry of Tea, In: Phenolic Compounds in Food and Their Effects on Health I. Ho Ch-T, Lee Ch Y, Huang M-T (Eds) Am Chem Soc, Washington, DC, Pp, pp. 102-117, (1992)
  • [8] Bilyk A., Cooper P.L., Sapers G.M., Varietal Differences in Distribution of Quercetin and Kaempferol in Onion (Allium cepa L.) Tissue, J Agric Food Chem, 32, pp. 274-276, (1984)
  • [9] Bilyk A., Sapers G.M., Distribution of Quercetin and Kaempferol in Lettuce Kale, Chive, Garlic Chive, Leek, Horseradish, Red Radish, and Red Cabbage Tissues, J Agric Food Chem, 33, pp. 226-228, (1985)
  • [10] Block G., Patterson B., Subar A., Fruit Vegetables, and Cancer Prevention: A Review of the Epidemiological Evidence, Nutrition and Cancer, 18, pp. 1-29, (1992)