Flavonols, flavones and anthocyanins as native antioxidants of food and their possible role in the prevention of chronic diseases [Flavonole, flavone und anthocyane als naturliche antioxidantien der nahrung und ihre mogliche rolle bei der pravention chronischer erkrankungen]

被引：105

作者：

Böhm H. ^{[1
]}

Boeing H. ^{[1
]}

Hempel J. ^{[1
]}

Raab B. ^{[1
]}

Kroke A. ^{[1
]}

机构：

[1] Deutsches Institut für Ernährungsforschung,

[2] Arthur-Schenuert-Allee 114–116,undefined

[3] D-14558 Bergholz-Rehbrücke,undefined

来源：

European Journal of Nutrition | 1998年 / 37卷 / 2期

关键词：

Anthocyanins; Antioxidative effects; Bioavailability; Flavones; Flavonoids; Flavonols; Prevention;

D O I：

10.1007/PL00007376

中图分类号：

学科分类号：

摘要：

Flavonoids are non-nutritive compounds of plants that have been intensively investigated during the past years due to their possible protective effects against chronic diseases. In vitro studies were able to demonstrate for flavonols, flavones, and most recently also for anthocyanins a considerable antioxidative activity, mainly based on scavenging of oxygen radicals. Flavonols and anthocyanins are commonly found in European fruits and vegetables. In addition, black tea and red wine may have a high content of these compounds. Those food items are the main sources of flavonol consumption each contributing to a different degree to the overall intake. The absorption of aglycones has been established before. However, only recently could the absorption of flavonolglycosides be demonstrated. The mean intake of flavonols of the German population was calculated using data from the National German Food Consumption Survey. According to this analysis, the daily per capita intake was about 11.5 mg flavonols, mainly derived from fruits and vegetables, but also from black tea and red wine. Epidemiological studies have been directed to investigate the association between flavonol consumption and disease risk. An inverse association between flavonol intake and mortality from myocardial infarction was observed. According to one of three studies, the flavonoid intake can be inversely correlated with cancer risk. This review summarizes the current knowledge on the occurrence, intake, bioavailability, and antioxidative properties of flavonols, flavones, and anthocyanins as well as the associations between flavonol intake and disease risks. Possible health related effects especially of flavonols are critically reflected, and the necessity of further research is outlined.

引用

页码：147 / 163

页数：16

共 144 条

[91] Paganga G., Rice-Evans C.A., The identification of flavonoids as glycosides in human plasma, FEES Lett, 401, pp. 78-82, (1997)
[92] Paul B.S., Pike L.M., Distribution of Quercetin Content in Different Rings of Various Coloured Onion (Allium cepa L) Cultivars, Horticult Science, 70, pp. 643-650, (1995)
[93] Paul B.S., Pike L.M., Hamilton B.K., Changes in Quercetin Concentration in Onion (Allium cepa L) Owing to Location, Growth Stage and Soil Type, New Phytologist, 130, pp. 349-355, (1995)
[94] Patil B.S., Pike L.M., Yoo K.S., Variation in thé Quercetin Conent in Different Colored Onions (Allium cepa L), Horticult Science, 120, pp. 909-913, (1995)
[95] Pincemail J., Deby C., Thirion A., De Bruyn-Dister M., Goutier R., Human myeloperoxidase activity is inhibited in vitro by quercetin, Comparison with Three Related Compounds. Experientia, 44, pp. 450-452, (1988)
[96] Pool-Zobel B.L., Mutagene und Carcinogene in Lebensmitteln, Lebensrnittelchemie, 44, pp. 133-139, (1990)
[97] Price K.R., Bacon J.R., Mjc R., Effect of Storage and Domestic Processing on the Content and Composition of Flavonol Glucosides in Onion (Allium cepa), J Agric Food Chem, 45, pp. 938-942, (1997)
[98] Raab B., Hempel J., Bohm H., Antioxidative potencies of flavonoids from vegetables as compared with their efficacies against oxidative stress. 2nd Intern Conf Clin Chemilumin Berlin: Abstr, (1996)
[99] Raab B., Hempel J., Bohm H., Antioxidative and antigenotoxic properties of flavonoids from beans (Phaseolus vulgaris L.), In: Food Factors for Cancer Prevention. Ohigashi H, Osawa T, Terao J, Watanabe S, Yoshikawa T (Eds) Springer Verlag, Tokyo Berlin Heidelberg, Pp, pp. 309-312, (1997)
[100] Rahman A., Fazal F., Greensill J., Ainley K., Parish J.H., Hadi S.M., Strand scission in DNA induced by dietary flavonoidsrrole of Cu(I) and oxygen free radicals and biological consequences of scission, Mol Cell Biochera, 111, pp. 3-9, (1992)

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