Stressful life events, personal losses, and perimenopase-related depression

被引：54

作者：

Schmidt P.J. ^{[1
,2
]}

Murphy J.H. ^{[1
]}

Haq N. ^{[1
]}

Rubinow D.R. ^{[1
]}

Danaceau M.A. ^{[1
]}

机构：

[1] Behavioral Endocrinology Branch, National Institutes of Health, Dept. of Health and Human Services, Bethesda, MD

[2] National Institutes of Health, Dept. of Health and Human Services, Behavioral Endocrinology Branch, Bethesda, MD 20892-1276

来源：

Archives of Women’s Mental Health | 2004年 / 7卷 / 1期

关键词：

Depression; Life events; Midlife; Perimenopause;

D O I：

10.1007/s00737-003-0036-2

中图分类号：

学科分类号：

摘要：

We compared the number and quality of life events reported by depressed perimenopausal women and a non-depressed comparison group. Additionally, we examined the effects of the presence of hot flushes on life event reports. All women were 44-55 years old, had irregular menses and elevated plasma gonadotropin levels. The Psychiatric Epidemiology Research Interview recorded both the frequency of occurrence and the desirability of life events experienced by the women during the six months prior to the interview. Depressed perimenopausal women (n = 50) reported significantly more undesirable events [Student's t-test (unpaired) with Bonferroni correction, t98 = 3.9, p= 0.001] but not more exit events (e.g., divorce, last child leaving home or death in family) (t98 = 0.9, p = NS) compared to the non-depressed women (n = 50). There were no effects of hot flushes on these diagnostic differences. The "empty nest" syndrome does not appear to be relevant in the development of perimenopausal depression. Nevertheless, independent of the presence of hot flushes, perimenopausal depressed women are more likely to report both negative life events and diminished self esteem.

引用

页码：19 / 26

页数：7

共 36 条

[11] Dohrenwend B.S., Krasnoff L., Askenasy A.R., Dohrenwend B.P., Exemplification of a method for scaling life events. The PERI Life Events Scale, J Health Soc Behav, 19, pp. 205-229, (1978)
[12] Ezquiaga E., Gutierrez J.L.A., Loepz A.G., Psychosocial factors and episode number in depression, J Affect Disord, 12, pp. 135-138, (1987)
[13] Greene J.G., Bereavement and social support at the climacteric, Maturitas, 5, pp. 115-124, (1983)
[14] Greene J.G., Cooke D.J., Life stress and symptoms at the climacterium, Br J Psychiatry, 136, pp. 486-491, (1980)
[15] Halbreich U., Endicott J., Schacht S., Nee J., The diversity of premenstrual changes as reflected in the Premenstrual Assessment Form, Acta Psychiatr Scand, 65, pp. 47-65, (1982)
[16] Holmes T.H., Rahe R.H., The social readjustment rating scale, J Psychosom Res, 11, pp. 213-218, (1967)
[17] Joffe H., Hall J.E., Soares C.N., Hennen J., Reilly C.J., Carlson K., Cohen L.S., Vasomotor symptoms are associated with depression in perimenopausal women seeking primary care, Menopause, 9, pp. 392-398, (2002)
[18] Judd L.L., Paulus M.P., Wells K.B., Rapaport M.H., Socioeconomic burden of subsyndromal depressive symptoms and major depression in a sample of the general population, Am J Psychiatry, 153, pp. 1411-1417, (1996)
[19] Kendler K.S., Thornton L.M., Gardner C.O., Stressful life events and previous episodes in the etiology of major depression in women: An evaluation of the "kindling" hypothesis, Am J Psychiatry, 157, pp. 1243-1251, (2000)
[20] Locke H.J., Wallace K.M., Short marital-adjustment and prediction tests: Their reliability and validity, Marr Fam Liv, 21, pp. 251-255, (1959)

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