胆汁淤积发生机制的研究进展

被引:8
作者
谌洁
章述军
机构
[1] 重庆医科大学附属第一医院感染科
关键词
胆汁淤积; 肝内胆汁淤积; 胆汁淤积性肝病; 综述;
D O I
暂无
中图分类号
R575 [肝及胆疾病];
学科分类号
100201 [内科学];
摘要
胆汁淤积是一种临床常见的症候群,根据发病部位不同可分为肝外胆汁淤积(EHC)及肝内胆汁淤积(IHC)。EHC主要由炎性水肿、结石、肿瘤及蛔虫等因素所致的胆道梗阻引起,而IHC的发生机制较为复杂,具体的发病机制尚不清楚,IHC包括原发性胆汁性胆管炎(PBC)、原发性硬化性胆管炎(PSC)、妊娠期肝内胆汁淤积症(ICP)、IgG4相关硬化性胆管炎、进行性家族性肝内胆汁淤积症在内的原发性IHC,以及由酒精性肝病、慢性病毒性肝炎、药物性肝损伤等引起的继发性IHC。本文主要总结胆汁淤积的发病机制研究新进展,旨在为该病的科研及临床工作者提供参考。
引用
收藏
页码:1074 / 1079
页数:6
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