降钙素原对感染性休克患者预后判断的价值

被引：22

作者：

郜杨 ^{[1
]}

康凯 ^{[2
]}

左姝 ^{[1
]}

于凯江 ^{[1
]}

机构：

[1] 哈尔滨医科大学附属第二医院重症医学科

[2] 哈尔滨医科大学附属第一医院重症医学科

来源：

中国急救医学 | 2014年 / 34卷 / 12期

关键词：

降钙素原; 感染性休克; 预后;

D O I：

暂无

中图分类号：

R631.4 [];

学科分类号：

摘要：

目的评价外周血降钙素原(PCT)对ICU感染性休克患者预后判断的价值。方法回顾性分析2012-01～2013-01入住ICU的102例感染性休克患者,记录其入院第1、2、3、4、5天外周血PCT水平,根据28 d生存情况分为存活组和死亡组,比较两组患者的PCT水平,并评价其与APACHEⅡ评分、SOFA评分的相关性。结果存活组和死亡组患者第1、2、3天PCT水平比较差异无统计学意义,但死亡组患者第4、5天PCT水平明显高于存活组(P<0.05);死亡组乳酸、SOFA评分、APACHEⅡ评分明显高于存活组(P<0.05);入院第4天患者PCT水平与SOFA评分和APACHEⅡ评分呈正相关(r分别为0.389和0.393,P均<0.01);入院第5天患者PCT水平与SOFA评分和APACHEⅡ评分呈正相关(r分别为0.649和0.658,P均<0.01);PCT为2.0μg/L时敏感度为81.2%,特异度为72.8%。结论动态监测PCT水平的变化可以有效评估感染性休克患者的预后。

引用

页码：1064 / 1067

页数：4

共 9 条

[1] Cord blood procalcitonin and Interleukin-6 are highly sensitive and specific in the prediction of early-onset sepsis in preterm infants
Steinberger, Eva
Hofer, Nora
Resch, Bernhard
[J]. SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION, 2014, 74 (05) : 432 - 436
[2] Procalcitonin as a predictor of sepsis and outcome in severe trauma patients: A prospective study.[J].Nonika Rajkumari;Purva Mathur;Satyapriya Sharma;Babita Gupta;Sanjeev Bhoi;Mahesh Misra.Journal of Laboratory Physicians.2013, 2
[3] Use of Serum Procalcitonin to Detect Bacterial Infection in Patients With Autoimmune Diseases A Systematic Review and Meta-Analysis
Wu, Jiunn-Yih
Lee, Si-Huei
Shen, Chih-Jung
Hsieh, Yueh-Che
Yo, Ping-Hsiung
Cheng, Hsiang-Yun
Chan, Rai-Chi
Lee, Chien-Chang
Chang, Shy-Shin
[J]. ARTHRITIS AND RHEUMATISM, 2012, 64 (09): : 3034 - 3042
[4] PCT as a diagnostic and prognostic tool in burn patients. Whether time course has a role in monitoring sepsis treatment.[J].A. Lavrentieva;S. Papadopoulou;J. Kioumis;E. Kaimakamis;M. Bitzani.Burns.2011, 3
[5] Circulating procalcitonin in aseptic carcinoma patients: a specificity study with <sup>18</sup>F-fluorodeoxyglucose positron-emission tomography/computed tomography as benchmark.[J].Luca Giovanella;Sergio Suriano;Riccardo Ricci;Paolo Ravani;Luca Ceriani.Clinical Chemistry and Laboratory Medicine.2010, 8
[6] Prognostic value of procalcitonin (PCT) and/or interleukin-6 (IL-6) plasma levels after multiple trauma for the development of multi organ dysfunction syndrome (MODS) or sepsis
Haasper, C.
Kalmbach, M.
Dikos, G. D.
Meller, R.
Mueller, C.
Krettek, C.
Hildebrand, F.
Frink, M.
[J]. TECHNOLOGY AND HEALTH CARE, 2010, 18 (02) : 89 - 100
[7] Procalcitonin (PCT)-guided algorithm reduces length of antibiotic treatment in surgical intensive care patients with severe sepsis: results of a prospective randomized study
Schroeder, S.
Hochreiter, M.
Koehler, T.
Schweiger, A. -M.
Bein, B.
Keck, F. S.
von Spiegel, T.
[J]. LANGENBECKS ARCHIVES OF SURGERY, 2009, 394 (02) : 221 - 226
[8] Procalcitonin increase in early identification of critically ill patients at high risk of mortality
Jensen, Jens Ulrik
Heslet, Lars
Jensen, Tom Hartvig
Espersen, Kurt
Steffensen, Peter
Tvede, Michael
[J]. CRITICAL CARE MEDICINE, 2006, 34 (10) : 2596 - 2602
[9] 降钙素原对急诊脓毒症患者早期诊断的价值
刘慧琳
刘桂花
马青变
[J]. 中国危重病急救医学, 2012, (05)

← 1 →