WOUND MANAGEMENT WITH N-CARBOXYBUTYL CHITOSAN

被引：115

作者：

BIAGINI, G

BERTANI, A

MUZZARELLI, R

DAMADEI, A

DIBENEDETTO, G

BELLIGOLLI, A

RICCOTTI, G

ZUCCHINI, C

RIZZOLI, C

机构：

[1] UNIV ANCONA,FAC MED,INST BIOCHEM,I-60100 ANCONA,ITALY

[2] UNIV ANCONA,FAC MED,INST HUMAN MORPHOL,I-60100 ANCONA,ITALY

[3] UNIV ANCONA,FAC MED,DERMATOL CLIN,I-60100 ANCONA,ITALY

[4] UNIV ANCONA,FAC MED,PLAST & RECONSTRUCT SURG CLIN,I-60100 ANCONA,ITALY

来源：

BIOMATERIALS | 1991年 / 12卷 / 03期

关键词：

CHITOSAN; WOUND DRESSINGS; TISSUE REPAIR;

D O I：

10.1016/0142-9612(91)90035-9

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

In patients undergoing plastic surgery, donor sites were treated with soft pads of freeze-dried N-carboxybutyl chitosan to promote ordered tissue regeneration. Compared to control donor sites, better histoarchitectural order, better vascularization and the absence of inflammatory cells were observed at the dermal level, whilst fewer aspects of proliferation of the malpighian layer were reported at the epidermal level. Accordingly, N-carboxybutyl chitosan leads to formation of regularly organized cutaneous tissue and reduces anomalous healing.

引用

页码：281 / 286

页数：6

共 18 条

[1] MORPHOLOGICAL-STUDY OF THE CAPSULAR ORGANIZATION AROUND TISSUE EXPANDERS COATED WITH N-CARBOXYBUTYL CHITOSAN [J].