SIGNIFICANT STRUCTURAL AND FUNCTIONAL CHANGE OF AN ANTIGEN-BINDING SITE BY A DISTANT AMINO-ACID SUBSTITUTION - PROPOSAL OF A STRUCTURAL MECHANISM

被引：72

作者：

CHIEN, NC

ROBERTS, VA

GIUSTI, AM

SCHARFF, MD

GETZOFF, ED

机构：

[1] YESHIVA UNIV ALBERT EINSTEIN COLL MED, DEPT CELL BIOL, BRONX, NY 10461 USA

[2] SCRIPPS CLIN & RES FDN, RES INST, DEPT MOLEC BIOL, LA JOLLA, CA 92037 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1989年 / 86卷 / 14期

关键词：

D O I：

10.1073/pnas.86.14.5532

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：5532 / 5536

页数：5

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