RELATIONSHIP BETWEEN THE PHARMACOLOGICAL ACTIVITY OF ANTITUMOR DRUGS AMETANTRONE AND MITOXANTRONE (NOVATRONE) AND THEIR ABILITY TO CONDENSE NUCLEIC-ACIDS

被引：114

作者：

KAPUSCINSKI, J

DARZYNKIEWICZ, Z

机构：

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1986年 / 83卷 / 17期

关键词：

D O I：

10.1073/pnas.83.17.6302

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：6302 / 6306

页数：5

共 32 条

[11] INCREASED ACCESSIBILITY OF BASES IN DNA UPON BINDING OF ACRIDINE-ORANGE [J].

KAPUSCINSKI, J ;

DARZYNKIEWICZ, Z .

NUCLEIC ACIDS RESEARCH, 1983, 11 (21) :7555-7568

[12] INTERACTIONS OF ACRIDINE-ORANGE WITH NUCLEIC-ACIDS - PROPERTIES OF COMPLEXES OF ACRIDINE-ORANGE WITH SINGLE STRANDED RIBONUCLEIC-ACID [J].

KAPUSCINSKI, J ;

DARZYNKIEWICZ, Z ;

MELAMED, MR .

BIOCHEMICAL PHARMACOLOGY, 1983, 32 (24) :3679-3694

[13]

KAPUSCINSKI J, 1982, CYTOMETRY, V2, P201

[14] DENATURATION OF NUCLEIC-ACIDS INDUCED BY INTERCALATING AGENTS - BIOCHEMICAL AND BIOPHYSICAL PROPERTIES OF ACRIDINE-ORANGE DNA COMPLEXES [J].

KAPUSCINSKI, J ;

DARZYNKIEWICZ, Z .

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 1984, 1 (06) :1485-&

[15] INTERACTIONS OF ANTITUMOR AGENTS AMETANTRONE AND MITOXANTRONE (NOVATRONE) WITH DOUBLE-STRANDED DNA [J].

KAPUSCINSKI, J ;

DARZYNKIEWICZ, Z .

BIOCHEMICAL PHARMACOLOGY, 1985, 34 (24) :4203-4213

[16] CONDENSATION OF NUCLEIC-ACIDS BY INTERCALATING AROMATIC CATIONS [J].

KAPUSCINSKI, J ;

DARZYNKIEWICZ, Z .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (23) :7368-7372

[17] INTERACTIONS OF A NEW ANTI-TUMOR AGENT,1,4-DIHYDROXY-5,8-BIS[[2-[(2-HYDROXYETHYL)AMINO]-ETHYL]AMINO]-9,10-ANTHRACENEDIONE, WITH NUCLEIC-ACIDS [J].

KAPUSCINSKI, J ;

DARZYNKIEWICZ, Z ;

TRAGANOS, F ;

MELAMED, MR .

BIOCHEMICAL PHARMACOLOGY, 1981, 30 (03) :231-240

[18] RELATIONSHIP BETWEEN CYTO-TOXICITY AND DNA DAMAGE IN MAMMALIAN-CELLS TREATED WITH ANTHRACENEDIONE DERIVATIVES [J].

LOCHER, SE ;

MEYN, RE .

CHEMICO-BIOLOGICAL INTERACTIONS, 1983, 46 (03) :369-379

[19] CHARACTERISTICS OF THE BINDING OF THE ANTICANCER AGENTS MITOXANTRONE AND AMETANTRONE AND RELATED STRUCTURES TO DEOXYRIBONUCLEIC ACIDS [J].

LOWN, JW ;

MORGAN, AR ;

YEN, SF ;

WANG, YH ;

WILSON, WD .

BIOCHEMISTRY, 1985, 24 (15) :4028-4035

[20]

LOWN JW, 1984, MOL PHARMACOL, V25, P178

← 1 2 3 4 →