STABILIZATION OF THE TIGHT JUNCTION OF THE INTESTINAL CACO-2 CELL MONOLAYER BY MILK WHEY PROTEINS

被引：19

作者：

HASHIMOTO, K ^{[1
]}

TAKEDA, K ^{[1
]}

NAKAYAMA, T ^{[1
]}

SHIMIZU, M ^{[1
]}

机构：

[1] UNIV TOKYO, DEPT APPL BIOL CHEM, BUNKYO KU, TOKYO 113, JAPAN

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1995年 / 59卷 / 10期

关键词：

D O I：

10.1271/bbb.59.1951

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The tight junction (TJ) of the human intestinal Caco-2-SF monolayer was shown not to have been stably formed, TJ was stabilized by incubating the cell monolayer with beta-lactoglobulin (beta-Lg) and bovine serum albumin (BSA). Thus, the Caco-2-SF cell-culture system will provide a useful model for studying the factors which stabilize TJ and for investigating the mechanism of TJ regulation.

引用

页码：1951 / 1952

页数：2

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