CONVERGENT TOTAL SYNTHESIS OF THE MICHELLAMINES

被引：57

作者：

KELLY, TR

GARCIA, A

LANG, FR

WALSH, JJ

BHASKAR, KV

BOYD, MR

GOTZ, R

KELLER, PA

WALTER, R

BRINGMANN, G

机构：

[1] NCI,DRUG DISCOVERY RES & DEV LAB,FREDERICK,MD 21702

[2] UNIV WURZBURG,INST ORGAN CHEM,D-97074 WURZBURG,GERMANY

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 41期

关键词：

D O I：

10.1016/S0040-4039(00)78358-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The total synthesis of both michellamine A (1a) and B (1b), by consecutive construction first of the inner (non-stereogenic) axis and subsequently the two outer (stereogenic) axes in a highly convergent manner, is described. The michellamines are of considerable interest due to their pronounced anti-HIV activity.

引用

页码：7621 / 7624

页数：4

共 19 条

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