STEREOCHEMICAL STUDIES ON MEDICINAL AGENTS .20. ABSOLUTE-CONFIGURATION AND ANALGETIC POTENCY OF ALPHA-PROMEDOL ENANTIOMERS - ROLE OF C-4 CHIRAL CENTER IN CONFERRING STEREOSELECTIVITY IN AXIAL-PHENYL AND EQUATORIAL-PHENYL PRODINE CONGENERS

被引：41

作者：

FRIES, DS ^{[1
]}

PORTOGHESE, PS ^{[1
]}

机构：

[1] UNIV MINNESOTA,COLL PHARM,DEPT MED CHEM,MINNEAPOLIS,MN 55455

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1976年 / 19卷 / 09期

关键词：

D O I：

10.1021/jm00231a014

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1155 / 1158

页数：4

共 22 条

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[2] STEREOCHEMICAL STUDIES ON MEDICINAL AGENTS .17. SYNTHESIS, ABSOLUTE-CONFIGURATION, AND ANALGETIC POTENCY OF ENANTIOMERIC DIASTEREOMERS OF 3-ETHYL AND 3-PROPYL DERIVATIVES OF 1-METHYL-4-PHENYL-4-PROPIONOXYPIPERIDINE
BELL, KH
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[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1974, 17 (01) : 129 - 131
[3] STEREOCHEMICAL STUDIES ON MEDICINAL AGENTS .15. ABSOLUTE-CONFIGURATIONS AND ANALGETIC POTENCIES OF ENANTIOMERIC DIASTEREOMERS OF 3-ALLYL-1-METHYL-4-PHENYL-4-PROPIONOXYPIPERIDINE
BELL, KH
PORTOGHESE, PS
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1973, 16 (06) : 589 - 591
[4] BENTLEY R, 1969, MOLECULAR ASYMMETRY, V1, pCH4
[5] STRUCTURAL STUDIES OF SYNTHETIC ANALGETICS .3. CRYSTAL AND MOLECULAR-STRUCTURE OF RHOMBOHEDRAL FORM OF (+/-)-BETA-PROMEDOL ALCOHOL
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AHMED, FR
[J]. ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE, 1972, 28 (DEC15): : 3484 - 3489
[6] STRUCTURAL STUDIES OF SYNTHETIC ANALGETICS .2. CRYSTAL AND MOLECULAR STRUCTURE OF MONOCLINIC FORM OF (+/-)-BETA-PROMEDOL ALCOHOL
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AHMED, FR
[J]. ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL CRYSTALLOGRAPHY AND CRYSTAL CHEMISTRY, 1972, B 28 (06): : 1796 - &
[7] EDDY NB, 1953, J PHARMACOL EXP THER, V107, P385
[8] STEREOCHEMICAL STUDIES ON MEDICINAL AGENTS .18. ABSOLUTE-CONFIGURATION AND ANALGETIC POTENCY OF TRIMEPERIDINE ENANTIOMERS
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PORTOGHE.PS
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1974, 17 (09) : 990 - 993
[9] HELLERBACH J, 1966, SYNTHETIC ANALGESI 2
[10] C-13 MAGNETIC-RESONANCE - STEREOCHEMISTRY OF PHARMACOLOGICALLY ACTIVE "1,2,5-TRIMETHYL-4-PHENYL-PIPERIDINE DERIVATIVES
JONES, AJ
BEEMAN, CP
CASY, AF
MCERLANE, KM
[J]. CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1973, 51 (11): : 1790 - 1796

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