STEREOCHEMICAL STUDIES ON MEDICINAL AGENTS .20. ABSOLUTE-CONFIGURATION AND ANALGETIC POTENCY OF ALPHA-PROMEDOL ENANTIOMERS - ROLE OF C-4 CHIRAL CENTER IN CONFERRING STEREOSELECTIVITY IN AXIAL-PHENYL AND EQUATORIAL-PHENYL PRODINE CONGENERS

被引：41

作者：

FRIES, DS ^{[1
]}

PORTOGHESE, PS ^{[1
]}

机构：

[1] UNIV MINNESOTA,COLL PHARM,DEPT MED CHEM,MINNEAPOLIS,MN 55455

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1976年 / 19卷 / 09期

关键词：

D O I：

10.1021/jm00231a014

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1155 / 1158

页数：4

共 22 条

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[17] STEREOCHEMICAL STUDIES ON MEDICINAL AGENTS .13. CORRELATION OF SOLID-STATE CONFORMATIONS OF 1,3,5-TRIMETHYL-4-PHENYL-4-PROPIONOXYPIPERIDINE AND 1,3-DIMETHYL-4-PHENYL-4-PROPIONOXYPIPERIDINE ENANTIOMERS WITH THEIR ABSOLUTE STEREOSELECTIVITY AT ANALGETIC RECEPTORS
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[18] A NEW CONCEPT ON MODE OF INTERACTION OF NARCOTIC ANALGESICS WITH RECEPTORS
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[19] STEREOCHEMICAL STUDIES ON MEDICINAL AGENTS .19. X-RAY CRYSTAL-STRUCTURES OF 2 (+ OR -)-ALLYLPRODINE DIASTEREOMERS - ROLE OF ALLYL GROUP IN CONFERRING HIGH STEREOSELECTIVITY AND POTENCY AT ANALGETIC RECEPTORS
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[20] PORTOGHESE PS, 1974, MOLECULAR QUANTUM PH, P349

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