ELF4 as a Central Gene in the Circadian Clock

被引:18
作者
Kolmos, Elsebeth [1 ]
Davis, Seth J. [1 ]
机构
[1] Max Planck Inst Plant Breeding Res, Dept Plant Dev Biol, Carl von Linne Weg 10, D-50829 Cologne, Germany
关键词
circadian clock; entrainment; ELF4; CCA1; LHY; TOC1; feedback loop;
D O I
10.4161/psb.2.5.4463
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The light-dark cycle of the environment serves as one of the major Zeitgebers in entrainment of the circadian clock. The circadian system consists of interconnected feedback loops in which the CCA1/LHY-TOC1 loop has a central position. Genetic analyses of the elf4 mutant suggested that it is a positive regulator of CCA1 and LHY expression. Recently, we refined the mode-of-action of ELF4 in entrainment of the clock, and here hypothesize that ELF4 expression is interlocked with the CCA1/LHY-TOC1 loop.
引用
收藏
页码:370 / 372
页数:3
相关论文
共 22 条
[1]   Critical role for CCA1 and LHY in maintaining circadian rhythmicity in Arabidopsis [J].
Alabadí, D ;
Yanovsky, MJ ;
Más, P ;
Harmer, SL ;
Kay, SA .
CURRENT BIOLOGY, 2002, 12 (09) :757-761
[2]   A complex genetic interaction between Arabidopsis thaliana TOC1 and CCA1/LHY in driving the circadian clock and in output regulation [J].
Ding, Zhaojun ;
Doyle, Mark R. ;
Amasino, Richard M. ;
Davis, Seth J. .
GENETICS, 2007, 176 (03) :1501-1510
[3]   The ELF4 gene controls circadian rhythms and flowering time in Arabidopsis thaliana [J].
Doyle, MR ;
Davis, SJ ;
Bastow, RM ;
McWatters, HG ;
Kozma-Bognár, L ;
Nagy, F ;
Millar, AJ ;
Amasino, RM .
NATURE, 2002, 419 (6902) :74-77
[4]   GIGANTEA:: a circadian clock-controlled gene that regulates photoperiodic flowering in Arabidopsis and encodes a protein with several possible membrane-spanning domains [J].
Fowler, S ;
Lee, K ;
Onouchi, H ;
Samach, A ;
Richardson, K ;
Coupland, G ;
Putterill, J .
EMBO JOURNAL, 1999, 18 (17) :4679-4688
[5]   The molecular basis of temperature compensation in the Arabidopsis circadian clock [J].
Gould, PD ;
Locke, JCW ;
Larue, C ;
Southern, MM ;
Davis, SJ ;
Hanano, S ;
Moyle, R ;
Milich, R ;
Putterill, J ;
Millar, AJ ;
Hall, A .
PLANT CELL, 2006, 18 (05) :1177-1187
[6]   Conditional circadian dysfunction of the Arabidopsis early-flowering 3 mutant [J].
Hicks, KA ;
Millar, AJ ;
Carre, IA ;
Somers, DE ;
Straume, M ;
MeeksWagner, DR ;
Kay, SA .
SCIENCE, 1996, 274 (5288) :790-792
[7]   EARLY FLOWERING3 encodes a novel protein that regulates circadian clock function and flowering in Arabidopsis [J].
Hicks, KA ;
Albertson, TM ;
Wagner, DR .
PLANT CELL, 2001, 13 (06) :1281-1292
[8]   Characterization of the APRR9 pseudo-response regulator belonging to the APRR1/TOC1 quintet in Arabidopsis thaliana [J].
Ito, S ;
Matsushika, A ;
Yamada, H ;
Sato, S ;
Kato, T ;
Tabata, S ;
Yamashino, T ;
Mizuno, T .
PLANT AND CELL PHYSIOLOGY, 2003, 44 (11) :1237-1245
[9]   Arabidopsis PSEUDO-RESPONSE REGULATOR7 is a signaling intermediate in phytochrome-regulated seedling deetiolation and phasing of the circadian clock [J].
Kaczorowski, KA ;
Quail, PH .
PLANT CELL, 2003, 15 (11) :2654-2665
[10]   EARLY FLOWERING 4 functions in phytochrome B-regulated seedling de-etiolation [J].
Khanna, R ;
Kikis, EA ;
Quail, PH .
PLANT PHYSIOLOGY, 2003, 133 (04) :1530-1538