ELF4 as a Central Gene in the Circadian Clock

被引:18
作者
Kolmos, Elsebeth [1 ]
Davis, Seth J. [1 ]
机构
[1] Max Planck Inst Plant Breeding Res, Dept Plant Dev Biol, Carl von Linne Weg 10, D-50829 Cologne, Germany
关键词
circadian clock; entrainment; ELF4; CCA1; LHY; TOC1; feedback loop;
D O I
10.4161/psb.2.5.4463
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The light-dark cycle of the environment serves as one of the major Zeitgebers in entrainment of the circadian clock. The circadian system consists of interconnected feedback loops in which the CCA1/LHY-TOC1 loop has a central position. Genetic analyses of the elf4 mutant suggested that it is a positive regulator of CCA1 and LHY expression. Recently, we refined the mode-of-action of ELF4 in entrainment of the clock, and here hypothesize that ELF4 expression is interlocked with the CCA1/LHY-TOC1 loop.
引用
收藏
页码:370 / 372
页数:3
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