PROTECTION OF PRIMARY AMINO AS PYRROLE IN ORGANOMETALLIC REAGENTS

被引：15

作者：

DAVIS, AP

EGAN, TJ

机构：

[1] Department of Chemistry, Trinity College, Dublin

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 52期

关键词：

D O I：

10.1016/S0040-4039(00)74737-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Pyrrole 5 was converted into Grignard and organocuprate reagents. After addition of the latter to alkene 6, the pyrrole ring was converted to a primary amine by ozonolysis, reduction and hydrolysis.

引用

页码：8125 / 8126

页数：2

共 8 条

[1] SYNTHESIS OF STEROIDAL CYCLODIMERS FROM CHOLIC-ACID - A MOLECULAR FRAMEWORK WITH POTENTIAL FOR RECOGNITION AND CATALYSIS [J].

BONARLAW, RP ;

DAVIS, AP .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1989, (15) :1050-1052

[2] THE BENZOSTABASE PROTECTING GROUP FOR PRIMARY AMINES - APPLICATION TO AROMATIC-AMINES [J].

BONARLAW, RP ;

DAVIS, AP ;

DORGAN, BJ .

TETRAHEDRON LETTERS, 1990, 31 (46) :6721-6724

[3] PROTECTION OF PRIMARY AMINES AS N-SUBSTITUTED 2,5-DIMETHYLPYRROLES [J].

BRUEKELMAN, SP ;

LEACH, SE ;

MEAKINS, GD ;

TIREL, MD .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1984, (12) :2801-2807

[4] SYNTHESIS AND X-RAY CRYSTAL-STRUCTURE OF A NEW CHOLAPHANE WITH EXTERNALLY DIRECTED FUNCTIONALITY [J].

DAVIS, AP ;

ORCHARD, MG ;

SLAWIN, AMZ ;

WILLIAMS, DJ .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1991, (09) :612-614

[5]

GREENE TW, 1991, PROTECTIVE GROUPS OR, P350

[6] N-ALKYLATION OF INDOLE AND PYRROLES IN DIMETHYL SULFOXIDE [J].

HEANEY, H ;

LEY, SV .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1973, (05) :499-500

[7]

KASHIMA C, 1988, J CHEM RES-S, P62

[8]

KASHIMA C, 1988, J CHEM RES M, P601

← 1 →