AN EXPEDITIOUS SYNTHESIS OF HOMOCHIRAL (R) 2-(9-PURINYL)BUTANE-1,4-DIOLS FROM (S) BUTANE-1,2,4-TRIOL

被引：10

作者：

PERBOST, M ^{[1
]}

LUCAS, M ^{[1
]}

CHAVIS, C ^{[1
]}

IMBACH, JL ^{[1
]}

机构：

[1] UNIV MONTPELLIER 2, CNRS, CHIM BIOORGAN LAB 488, CASE 008, F-34095 MONTPELLIER 5, FRANCE

来源：

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS | 1992年 / 11卷 / 08期

关键词：

D O I：

10.1080/07328319208021193

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The synthesis of (R) 2-(9-adenyl) and (R) 2-(9-guanyl)butane-1, 4-diols are described via an alkylation reaction of 6-chloropurine and N2-acetyl-O6-diphenylcarbamoyl guanine by (S) 1, 4-di-tert-butyldiphenylsilyloxybutane-2-ol under Mitsunobu conditions.

引用

页码：1529 / 1537

页数：9

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