LETS STOP THE COMEBACK OF TUBERCULOSIS - BEST DRUG REGIMENS FOR PREVENTION AND TREATMENT

被引：4

作者：

AMIN, NM

机构：

[1] UNIV CALIF LOS ANGELES,SCH MED,LOS ANGELES,CA 90024

[2] KERN MED CTR,DEPT PEDIAT,BAKERSFIELD,CA 93305

[3] UNIV CALIF IRVINE,CALIF COLL MED,IRVINE,CA 92717

来源：

POSTGRADUATE MEDICINE | 1990年 / 88卷 / 06期

关键词：

D O I：

10.1080/00325481.1990.11716425

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Tuberculosis has been on the increase in recent years, so physicians need to be aware of it once again. Very effective drugs are available to treat the disease. Pharmacokinetics, dosing schedule, and adverse reactions of each anti-tuberculous agent need to be considered. A short (6-month) course of therapy is now recommended: Isoniazid, rifampin (Rifadin, Rimactane), and pyrazinamide are given for the initial 2 months, followed by isoniazid and rifampin for 4 months. If drug resistance is a factor, a fourth drug is added to the initial regimen, and therapy may have to be extended. Chemoprophylaxis with isoniazid is very important to reduce the incidence of tuberculosis. It should be given to all high-risk persons.

引用

页码：107 / &