SIMULTANEOUS GENETIC-ANALYSIS OF LONGITUDINAL MEANS AND COVARIANCE STRUCTURE IN THE SIMPLEX MODEL USING TWIN DATA

被引：21

作者：

DOLAN, CV ^{[1
]}

MOLENAAR, PCM ^{[1
]}

BOOMSMA, DI ^{[1
]}

机构：

[1] FREE UNIV AMSTERDAM,DEPT EXPTL PSYCHOL,1081 HV AMSTERDAM,NETHERLANDS

来源：

BEHAVIOR GENETICS | 1991年 / 21卷 / 01期

关键词：

REPEATED MEASURES; GENETIC AND ENVIRONMENTAL COVARIANCE STRUCTURE; MEAN TREND; LONGITUDINAL TWIN DATA; GENETIC SIMPLEX MODE; LISREL;

D O I：

10.1007/BF01067666

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

A longitudinal model based on the simplex model is presented to analyze simultaneously means and covariance structure using univariate longitudinal twin data. The objective of the model is to decompose the mean trend into components which can be attributed to those genetic and environmental factors which give rise to phenotypic individual differences and a component of unknown constitution which does not involve individual differences. Illustrations are given using simulated data and repeatedly measured weight obtained in a sample of 82 female twin pairs on six occasions.

引用

页码：49 / 65

页数：17

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