[1] MAX PLANCK INST PSYCHIAT,DEPT CLIN,KRAEPELINSTR 10,W-8000 MUNICH 40,GERMANY
来源:
PSYCHOSOMATIC MEDICINE
|
1990年
/
52卷
/
06期
关键词:
D O I:
10.1097/00006842-199011000-00008
中图分类号:
R749 [精神病学];
学科分类号:
100205 ;
摘要:
The heat pain threshold was measured with phasic and tonic stimuli under basal conditions and after naloxone administration in 10 anorectic and 10 bulimic patients as well as in 11 healthy control subjects. Under both kinds of stimulation, the basal threshold values were elevated in the bulimic patients and in some of the anorectic patients. Naloxone did not differ from placebo in its effect on the pain thresholds (phasic and tonic), suggesting that a nonopioid mechanism was responsible for the threshold elevation found in the eating disorder patients. The plasma cortisol concentration was similar in the three groups and not correlated with the basal pain thresholds in the patients. Other indicators of dieting such as β-hydroxybutric acid and triiodothyronine also showed no correlation with the basal pain thresholds. Significant height correlations can be interpreted as weak evidence that neuropathy is the cause of the increase in the pain threshold.