EVIDENCES FOR A SATIATING EFFECT OF DEFATTED JOJOBA MEAL

Supplementation of food with increasing doses (3, 5, and 10%) of defatted jojoba meal induced a pronounced dose-dependent food intake reduction in fasted and non-fasted rats. This effect was more pronounced in non-fasted than in fasted rats, which is typical for satiety agents. Water intake was reduced to the pair-fed level in non-fasted rats with free access to water and receiving food supplemented with 10% defatted jojoba meal. This was also observed in fasted rats deprived of water during the fasting period and receiving food supplemented with 10% defatted jojoba meal. The reduced water intake in defatted jojoba meal treated rats was entirely due to the food intake reduction. These observations are in favour of the hypothesis that defatted jojoba meal induces its food intake reduction by stimulating satiety. Possible mechanisms are discussed.