VAGINAL PROGESTERONE AS LUTEAL PHASE SUPPORT IN AN IVF GIFT PROGRAM

被引:18
作者
POLSON, DW [1 ]
ROGERS, PAW [1 ]
KRAPEZ, JA [1 ]
LEETON, JF [1 ]
机构
[1] MONASH IVF PROGRAMME,INFERTIL MED CTR,RICHMOND,VIC,AUSTRALIA
来源
EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY | 1992年 / 46卷 / 01期
关键词
VAGINAL PROGESTERONE; LUTEAL PHASE; IVF PROGRAM;
D O I
10.1016/0028-2243(92)90276-5
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
To determine whether luteal phase support with vaginal progesterone could improve pregnancy rates in our IVF/GIFT programme, we performed a prospective randomised controlled study. After stimulation with clomiphene citrate/ human menopausal gonadotrophin, 123 women received no luteal support and 122 received progesterone pessaries 100 mg b.d. from 48 hours prior to embryo transfer and continued throughout the luteal phase. There was no difference in the pregnancy rate following IVF/ET (6/58 and 10/58 for the pessary and control group respectively), but a significantly higher rate was noted for GIFT (13/34 and 5/42 for the pessary and control group respectively; P < 0.05). Of interest, only one of the 19 pregnancies using luteal support was extra-uterine, compared with 6/15 in the control group.
引用
收藏
页码:35 / 38
页数:4
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