CHROMIUM DETERMINATION BY SUPERCRITICAL-FLUID CHROMATOGRAPHY WITH INDUCTIVELY-COUPLED PLASMA-MASS SPECTROMETRIC AND FLAME IONIZATION DETECTION

被引:14
作者
CAREY, JM [1 ]
VELA, NP [1 ]
CARUSO, JA [1 ]
机构
[1] UNIV CINCINNATI,DEPT CHEM,CINCINNATI,OH 45221
关键词
D O I
10.1016/0021-9673(94)80520-2
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Supercritical fluid chromatography (SFC) has been investigated for the separation of a pair of beta-ketonate chromium compounds and a thermally labile organochromium dimer. A limited comparison between flame ionization detection (FID) and inductively coupled plasma mass spectrometric (ICP-MS) detection of these compounds is presented. The beta-ketonate complexes were observed with both detectors, while the thermally labile dimer was not observed with ICP-MS detection. Detection limits for these compounds with ICP-MS were in the range of 0.9 to 3 pg with FID giving values between 10 and 250 pg. Reproducibility of the method is between 1 and 4% relative standard deviation (R.S.D.). The technique provided a linear response over approximately three orders of magnitude. The effect of two mobile phases (nitrous oxide and carbon dioxide) on the detection by each of the detectors are presented in a qualitative manner. Finally, the SFC-ICP interface heating method and the manner in which the restrictor is heated in the FID system are compared and there effect on the chromatography discussed.
引用
收藏
页码:329 / 340
页数:12
相关论文
共 18 条
[1]   SEPARATION OF METAL-CONTAINING COMPOUNDS BY SUPERCRITICAL FLUID CHROMATOGRAPHY [J].
ASHRAFKHORASSANI, M ;
HELLGETH, JW ;
TAYLOR, LT .
ANALYTICAL CHEMISTRY, 1987, 59 (17) :2077-2081
[2]   ELECTROTHERMAL VAPORIZATION FOR SAMPLE INTRODUCTION IN PLASMA SOURCE SPECTROMETRY [J].
CAREY, JM ;
CARUSO, JA .
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY, 1992, 23 (05) :397-439
[3]   PLASMA SPECTROMETRIC DETECTION FOR SUPERCRITICAL FLUID CHROMATOGRAPHY [J].
CAREY, JM ;
CARUSO, JA .
TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 1992, 11 (08) :287-293
[4]   MULTIELEMENT DETECTION FOR SUPERCRITICAL FLUID CHROMATOGRAPHY BY INDUCTIVELY COUPLED PLASMA MASS-SPECTROMETRY [J].
CAREY, JM ;
VELA, NP ;
CARUSO, JA .
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY, 1992, 7 (08) :1173-1181
[5]   ALTERNATE METHODS OF SAMPLE INTRODUCTION FOR PLASMA-MASS SPECTROMETRY [J].
CAREY, JM ;
BYRDY, FA ;
CARUSO, JA .
JOURNAL OF CHROMATOGRAPHIC SCIENCE, 1993, 31 (08) :330-344
[6]  
FUJIMOTO C, 1990, J MICROCOLUMN SEP, V2, P146
[7]   REVERSED-PHASE HPLC OF BETA-DIKETONE METAL-CHELATES [J].
GURIRA, RC ;
CARR, PW .
JOURNAL OF CHROMATOGRAPHIC SCIENCE, 1982, 20 (10) :461-465
[8]  
HEITKEMPER DT, 1992, TRACE METAL ANAL SPE, pCH3
[9]  
JINNO K, 1990, HRC-J HIGH RES CHROM, V13, P13
[10]  
Klaassen C.D., 1986, TOXICOLOGY BASIC SCI, V3rd