CLINICAL ANALYSIS OF 40 CASES OF CHILDHOOD-ONSET BEHCET-DISEASE

被引：64

作者：

KIM, DK ^{[1
]}

CHANG, SN ^{[1
]}

BANG, D ^{[1
]}

LEE, ES ^{[1
]}

LEE, S ^{[1
]}

机构：

[1] YONSEI UNIV,COLL MED,DEPT DERMATOL,CPO BOX 8044,SEOUL,SOUTH KOREA

来源：

PEDIATRIC DERMATOLOGY | 1994年 / 11卷 / 02期

关键词：

D O I：

10.1111/j.1525-1470.1994.tb00559.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Behcet's disease is a chronic, relapsing, idiopathic, multisystem condition characterized by mucocutaneous, ocular, gastrointestinal, articular, vascular, urogenital, and neurologic involvement. Usually the onset occurs between 20 and 30 years of age; it is very uncommon in children. We analyzed 40 cases of childhood-onset Behcet's disease. The male:female ratio was 0.67. The most frequent major sign was oral ulceration, appearing in all patients. Other major signs were genital ulcers (33 patients), skin lesions (29), and ocular lesions (11). The average time interval between the initial oral ulceration and the second major manifestation was 8.8 years. After the second major manifestation, the third and fourth features rapidly developed within one to two years. The most frequent minor sign was arthritis, occurring in 11 of 40 patients. Intestinal, neurologic, and renal involvement was also present. From our results, we concluded that oral ulceration, which is the most common initial manifestation, should not be neglected in children, since it may signal Behcet's disease.

引用

页码：95 / 101

页数：7

共 47 条

[21]

Criteria for diagnosis of Behçet's disease, Lancet, 335, pp. 1078-1080, (1990)

[22]

Dong YI, Ming QX, Zhang NZ, Et al., Testing different diagnostic criteriaof Behçet's syndrome in Chinese patients, Behçet's disease :proceedings of the 5th international conference on Behçet's disease, pp. 55-59, (1991)

[23]

A nationwide survey of Behçet's disease in Japan, Jpn J Ophthalmol, 18, pp. 282-290, (1974)

[24]

Chajek T, Fainaru M., Behçet disease: report of 41 cases and a review of the literature, Medicine, 54, pp. 179-196, (1975)

[25]

Kim HJ, Bang D., Lee SH, Et al., Behçet's syndrome in Korea: a look at the clinical picture, Yonsei Med J, 29, pp. 72-78, (1988)

[26]

Cho MY, Lee SH, Bang D, Et al., Epidemiologic findings of Behçet's syndrome, Kor J Dermatol, 26, pp. 320-329, (1988)

[27]

Ohno S., Behçet's disease in the world, Recent advances in Behçet's disease

[28]

proceedings of the 4th international conference on Behçet's disease, pp. 181-186, (1986)

[29]

Behçet's disease presenting as chronic aphthous stomatitis in a child, Pediatrics, 62, pp. 205-208, (1978)

[30]

Ammann AJ, Johanson A, Fyfe GA, Et al., Behçet's syndrome, J Pediatr, 107, pp. 41-43, (1985)

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