MEIOTIC RECOMBINATION BETWEEN REPEATED TRANSPOSABLE ELEMENTS IN SACCHAROMYCES-CEREVISIAE

被引：64

作者：

KUPIEC, M ^{[1
]}

PETES, TD ^{[1
]}

机构：

[1] UNIV CHICAGO, DEPT MOLE GENET & CELL BIOL, CHICAGO, IL 60637 USA

来源：

MOLECULAR AND CELLULAR BIOLOGY | 1988年 / 8卷 / 07期

关键词：

D O I：

10.1128/MCB.8.7.2942

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have measured the frequency of meiotic recombination between marked Ty elements in the Saccharomyces cerevisiae genome. These recombination events were usually nonreciprocal (gene conversions) and sometimes involved nonhomologous chromosomes. The frequency of ectopic gene conversion among Ty elements appeared lower than expected on the basis of previous studies of recombination between artificially constructed repeats. The conversion events involved either a subset of the total Ty elements in the genome or the conversion tract was restricted to a small region of the Ty element. In addition, the observed conversion events were very infrequently associated with reciprocal exchange.

引用

页码：2942 / 2954

页数：13

共 54 条

[1]

[Anonymous], NEUROSCIENCE EVOLUTI

[2] TY ELEMENTS TRANSPOSE THROUGH AN RNA INTERMEDIATE [J].

BOEKE, JD ;

GARFINKEL, DJ ;

STYLES, CA ;

FINK, GR .

CELL, 1985, 40 (03) :491-500

[3] A POSITIVE SELECTION FOR MUTANTS LACKING OROTIDINE-5'-PHOSPHATE DECARBOXYLASE ACTIVITY IN YEAST - 5-FLUORO-OROTIC ACID RESISTANCE [J].

BOEKE, JD ;

LACROUTE, F ;

FINK, GR .

MOLECULAR & GENERAL GENETICS, 1984, 197 (02) :345-346

[4] STERILE HOST YEASTS (SHY) - EUKARYOTIC SYSTEM OF BIOLOGICAL CONTAINMENT FOR RECOMBINANT DNA EXPERIMENTS [J].

BOTSTEIN, D ;

FALCO, SC ;

STEWART, SE ;

BRENNAN, M ;

SCHERER, S ;

STINCHCOMB, DT ;

STRUHL, K ;

DAVIS, RW .

GENE, 1979, 8 (01) :17-24

[5] GENE CONVERSION AND RECIPROCAL EXCHANGE IN A TY-MEDIATED TRANSLOCATION IN YEAST [J].

BREILMANN, D ;

GAFNER, J ;

CIRIACY, M .

CURRENT GENETICS, 1985, 9 (07) :553-560

[6] SEPARATION OF CHROMOSOMAL DNA-MOLECULES FROM YEAST BY ORTHOGONAL-FIELD-ALTERNATION GEL-ELECTROPHORESIS [J].

CARLE, GF ;

OLSON, MV .

NUCLEIC ACIDS RESEARCH, 1984, 12 (14) :5647-5664

[7]

CASADABAN MJ, 1983, METHOD ENZYMOL, V100, P293

[8] GENETIC EVENTS ASSOCIATED WITH AN INSERTION MUTATION IN YEAST [J].

CHALEFF, DT ;

FINK, GR .

CELL, 1980, 21 (01) :227-237

[9]

CHATTOO BB, 1979, GENETICS, V93, P51

[10] ROLE OF CHROMOSOME TRANSLOCATIONS IN HUMAN NEOPLASIA [J].

CROCE, CM .

CELL, 1987, 49 (02) :155-156

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