INDUCTION OF THE PROTOONCOGENE C-JUN BY ANGIOTENSIN-II

被引：148

作者：

NAFTILAN, AJ ^{[1
]}

GILLILAND, GK ^{[1
]}

ELDRIDGE, CS ^{[1
]}

KRAFT, AS ^{[1
]}

机构：

[1] UNIV ALABAMA,DIV HEMATOL ONCOL,BIRMINGHAM,AL 35294

来源：

MOLECULAR AND CELLULAR BIOLOGY | 1990年 / 10卷 / 10期

关键词：

D O I：

10.1128/MCB.10.10.5536

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Angiotensin (Ang) II causes hypertrophy of rat aortic smooth muscle cells in culture and results in the rapid activation of c-fos. This study demonstrated that Ang II also activated c-jun and, in addition, could activate the AP-1 enhancer element. These data add support for a role of Ang II as an important mediator of vascular smooth muscle cell growth.

引用

页码：5536 / 5540

页数：5

共 41 条

[1] 12-O-TETRADECANOYL-PHORBOL-13-ACETATE INDUCTION OF THE HUMAN COLLAGENASE GENE IS MEDIATED BY AN INDUCIBLE ENHANCER ELEMENT LOCATED IN THE 5'-FLANKING REGION
ANGEL, P
BAUMANN, I
STEIN, B
DELIUS, H
RAHMSDORF, HJ
HERRLICH, P
[J]. MOLECULAR AND CELLULAR BIOLOGY, 1987, 7 (06) : 2256 - 2266
[2] ONCOGENE JUN ENCODES A SEQUENCE-SPECIFIC TRANS-ACTIVATOR SIMILAR TO AP-1
ANGEL, P
ALLEGRETTO, EA
OKINO, ST
HATTORI, K
BOYLE, WJ
HUNTER, T
KARIN, M
[J]. NATURE, 1988, 332 (6160) : 166 - 171
[3] VASCULAR WALL RENIN IN SPONTANEOUSLY HYPERTENSIVE RATS - POTENTIAL RELEVANCE TO HYPERTENSION MAINTENANCE AND ANTIHYPERTENSIVE EFFECT OF CAPTOPRIL
ASAAD, MM
ANTONACCIO, MJ
[J]. HYPERTENSION, 1982, 4 (04) : 487 - 493
[4] ANGIOTENSIN-II-STIMULATED PROTEIN-SYNTHESIS IN CULTURED VASCULAR SMOOTH-MUSCLE CELLS
BERK, BC
VEKSHTEIN, V
GORDON, HM
TSUDA, T
[J]. HYPERTENSION, 1989, 13 (04) : 305 - 314
[5] HUMAN PROTOONCOGENE C-JUN ENCODES A DNA-BINDING PROTEIN WITH STRUCTURAL AND FUNCTIONAL-PROPERTIES OF TRANSCRIPTION FACTOR AP-1
BOHMANN, D
BOS, TJ
ADMON, A
NISHIMURA, T
VOGT, PK
TJIAN, R
[J]. SCIENCE, 1987, 238 (4832) : 1386 - 1392
[6] BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3
[7] CABBOLD PH, 1987, BIOCHEM J, V248, P313
[8] THE C-FOS PROTEIN INTERACTS WITH C-JUN/AP-1 TO STIMULATE TRANSCRIPTION OF AP-1 RESPONSIVE GENES
CHIU, R
BOYLE, WJ
MEEK, J
SMEAL, T
HUNTER, T
KARIN, M
[J]. CELL, 1988, 54 (04) : 541 - 552
[9] EXPRESSION OF THE C-FOS GENE AND OF AN FOS-RELATED GENE IS STIMULATED BY PLATELET-DERIVED GROWTH-FACTOR
COCHRAN, BH
ZULLO, J
VERMA, IM
STILES, CD
[J]. SCIENCE, 1984, 226 (4678) : 1080 - 1082
[10] CURRAN T, 1987, ONCOGENE, V2, P79

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