INHIBITION OF STEROID 5-ALPHA-REDUCTASE FROM HUMAN-SKIN FIBROBLASTS BY 17-BETA-N,N-DIETHYLCARBAMOYL-4-METHYL-4-AZA-5-ALPHA-ANDROSTAN-3-ONE

被引：25

作者：

LESHIN, M

WILSON, JD

机构：

来源：

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY | 1982年 / 17卷 / 03期

关键词：

D O I：

10.1016/0022-4731(82)90196-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：245 / 250

页数：6

共 22 条

[1] INHIBITION OF TESTOSTERONE 5-ALPHA-REDUCTASE BY A PROPOSED ENZYME-ACTIVATED, ACTIVE SITE-DIRECTED INHIBITOR [J].

BLOHM, TR ;

METCALF, BW ;

LAUGHLIN, ME ;

SJOERDSMA, A ;

SCHATZMAN, GL .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1980, 95 (01) :273-280

[2] ATTENUATION BY A 5-ALPHA-REDUCTASE INHIBITOR OF THE ACTIVATIONAL EFFECT OF TESTOSTERONE PROPIONATE ON PENILE ERECTIONS IN CASTRATED MALE-RATS [J].

BRADSHAW, WG ;

BAUM, MJ ;

AWH, CC .

ENDOCRINOLOGY, 1981, 109 (04) :1047-1051

[3] RESPONSE OF RAT VENTRAL PROSTATE TO A NEW AND NOVEL 5ALPHA-REDUCTASE INHIBITOR [J].

BROOKS, JR ;

BAPTISTA, EM ;

BERMAN, C ;

HAM, EA ;

HICHENS, M ;

JOHNSTON, DBR ;

PRIMKA, RL ;

RASMUSSON, GH ;

REYNOLDS, GF ;

SCHMITT, SM ;

ARTH, GE .

ENDOCRINOLOGY, 1981, 109 (03) :830-836

[4] EFFECT OF A NEW 5-ALPHA-REDUCTASE INHIBITOR ON SIZE, HISTOLOGIC CHARACTERISTICS, AND ANDROGEN CONCENTRATIONS OF THE CANINE PROSTATE [J].

BROOKS, JR ;

BERMAN, D ;

GLITZER, MS ;

GORDON, LR ;

PRIMKA, RL ;

REYNOLDS, GF ;

RASMUSSON, GH .

PROSTATE, 1982, 3 (01) :35-44

[5]

BROWN MS, 1978, J BIOL CHEM, V253, P1121

[6] CLINICAL, ENDOCRINOLOGICAL, AND ENZYMATIC CHARACTERIZATION OF 2 PATIENTS WITH 5ALPHA-REDUCTASE DEFICIENCY - EVIDENCE THAT A SINGLE ENZYME IS RESPONSIBLE FOR 5-ALPHA-REDUCTION OF CORTISOL AND TESTOSTERONE [J].

FISHER, LK ;

KOGUT, MD ;

MOORE, RJ ;

GOEBELSMANN, U ;

WEITZMAN, JJ ;

ISAACS, H ;

GRIFFIN, JE ;

WILSON, JD .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1978, 47 (03) :653-664

[7]

FREDERIKSEN DW, 1971, J BIOL CHEM, V246, P2584

[8] SYNDROMES OF ANDROGEN RESISTANCE [J].

GRIFFIN, JE ;

WILSON, JD .

NEW ENGLAND JOURNAL OF MEDICINE, 1980, 302 (04) :198-209

[9] DIHYDROTESTOSTERONE BINDING BY CULTURED HUMAN FIBROBLASTS - COMPARISON OF CELLS FROM CONTROL SUBJECTS AND FROM PATIENTS WITH HEREDITARY MALE PSEUDOHERMAPHRODITISM DUE TO ANDROGEN RESISTANCE [J].

GRIFFIN, JE ;

PUNYASHTHITI, K ;

WILSON, JD .

JOURNAL OF CLINICAL INVESTIGATION, 1976, 57 (05) :1342-1351

[10] HEREDITARY MALE PSEUDOHERMAPHRODITISM ASSOCIATED WITH AN UNSTABLE FORM OF 5-ALPHA-REDUCTASE [J].

LESHIN, M ;

GRIFFIN, JE ;

WILSON, JD .

JOURNAL OF CLINICAL INVESTIGATION, 1978, 62 (03) :685-691

← 1 2 3 →