STRAINS OF MYCOBACTERIUM-TUBERCULOSIS DIFFER IN SUSCEPTIBILITY TO REACTIVE NITROGEN INTERMEDIATES IN-VITRO

被引：77

作者：

OBRIEN, L

CARMICHAEL, J

LOWRIE, DB

ANDREW, PW

机构：

[1] UNIV LEICESTER,DEPT MICROBIOL & IMMUNOL,LEICESTER LE1 9HN,LEICS,ENGLAND

[2] NATL INST MED RES,LEPROSY & MYCOBACTERIAL DIS LABS,LONDON,ENGLAND

来源：

INFECTION AND IMMUNITY | 1994年 / 62卷 / 11期

关键词：

D O I：

10.1128/IAI.62.11.5187-5190.1994

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The effects on the viability of Mycobacterium tuberculosis strains and one Mycobacterium bovis strain from exposure to sodium nitrite for 24 h, in both neutral and acidic media, were tested. The in vitro resistance of mycobacteria to reactive nitrogen intermediates, generated at an acidic pH, was found to have a significant (P < 0.05) positive correlation to the virulence of strains in guinea pigs.

引用

页码：5187 / 5190

页数：4

共 27 条

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