EXERTIONAL RHABDOMYOLYSIS IN A PATIENT WITH CALCIUM ADENOSINE-TRIPHOSPHATASE DEFICIENCY

被引：25

作者：

POELS, PJE

WEVERS, RA

BRAAKHEKKE, JP

BENDERS, AAGM

VEERKAMP, JH

JOOSTEN, EMG

机构：

[1] CATHOLIC UNIV NIJMEGEN,DEPT NEUROL,NIJMEGEN,NETHERLANDS

[2] CATHOLIC UNIV NIJMEGEN,DEPT BIOCHEM,NIJMEGEN,NETHERLANDS

[3] SOPHIA HOSP,ZWOLLE,NETHERLANDS

来源：

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 1993年 / 56卷 / 07期

关键词：

D O I：

10.1136/jnnp.56.7.823

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A patient with exertional rhabdomyolysis and continuously elevated serum creatine kinase (CK) was investigated. The known causes of recurrent attacks of rhabdomyolysis were ruled out by appropriate histochemical and biochemical investigations. During ischaemic exercise tests an abnormal K+-efflux from exercising muscles was observed. The patient was found to have a deficiency of muscular Ca2+-ATPase. Dantrolene sodium therapy gave relief of muscle symptoms and improved the exercise tolerance. Both the CK level and the K+-efflux in ischaemic forearm testing became normal on this therapy.

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页码：823 / 826

页数：4

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