LN(OTF)3-CATALYZED OR SC(OTF)(3)-CATALYZED 3 COMPONENTS COUPLING REACTIONS BETWEEN ALDEHYDES, AMINES, AND DIENES OR ALKENES - EFFICIENT SYNTHESES OF PYRIDINE AND QUINOLINE DERIVATIVES
Three components coupling reactions between aldehydes, amines, and dienes or alkenes were catalyzed by lanthanide or scandium triflate to afford pyridine and quinoline derivatives in high yields. The Lewis acid catalysts were stable and kept their activity even in the presence of water and amines.