A CONVENIENT AND VERSATILE SYNTHESIS OF PORPHOBILINOGEN

被引:16
作者
ADAMCZYK, M
REDDY, RE
机构
[1] Division Organic Chemistry Research (9NM, AP20), Diagnostics Division, Abbott Laboratories, Abbott Park, IL 60064-3500
关键词
D O I
10.1016/0040-4039(95)01979-R
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Porphobilinogen (PEG, 1) was synthesized from 2-cyano-3,4-substituted pyrrole 3, which was obtained by condensation of alpha-acetoxynitro compound 4b with isocyanoacetonitrile (5), via functional group transformation in good yield.
引用
收藏
页码:9121 / 9124
页数:4
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