共 21 条
[21]
WUTHRICH B, 1987, MANUALE ALLERGOLOGIC, V14, P1
MASTOCYTOSIS AND ATOPY - A STUDY OF 33 PATIENTS WITH URTICARIA-PIGMENTOSA
被引：51
作者：
MULLER, U
HELBLING, A
HUNZIKER, T
WUTHRICH, B
PECOUD, A
GILARDI, S
BERETTA, E
FASEL, J
MESSERLI, W
MAURER, P
机构：
[1] UNIV HOSP ZURICH,DEPT DERMATOL,DIV ALLERGY,CH-8091 ZURICH,SWITZERLAND
[2] INSELSPITAL BERN,DEPT DERMATOL,CH-3010 BERN,SWITZERLAND
[3] UNIV HOSP LAUSANNE,DIV IMMUNOL & ALLERGOL,LAUSANNE,SWITZERLAND
来源：
关键词：
atopy;
Hymenoptera venom allergy;
IgE;
Mastocytosis;
urticaria pigmentosa;
D O I：
10.1111/j.1398-9995.1990.tb00945.x
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
Thirty‐three patients with histologically verified urticaria pigmentosa were studied for coexisting atopi disease by means of history, skin prick testing with five common inhalants and serological investigation for total IgE and specific IgE antibodies to five common inhalants. The prevalence of atopy in urticaria pigmentosa was similar to that observed m the normal Swiss population, both on the basis of history (7/33 = 21 %) and of positive skin prick tests to common inhalants (12/33 = 36%). However, total serum IgE levels were significantly lower (geometric mean value 16.8 kU/l) than in a control group of 52 Swiss blood donors of comparable age and sex distribution (geometric mean value 43.0 kU/l, 2.93, P < 0.005). Specific IgE antibodies to common inhalants were also observed less frequently in urticaria pigmentosa patients than in controls, although this difference was not statistically significant. Low total and specific IgE values in patients with urticaria pigmentosa may be explained by increased absorption of circulating IgE to abundant tissue mast cells. Copyright © 1990, Wiley Blackwell. All rights reserved
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页码：597 / 603
页数：7
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