SYNTHESIS OF 5-(AROYLAMINO)-2-METHYL-2H-1,2,4-THIADIAZOL-3-ONES BY OXIDATIVE CYCLIZATION OF 1-AROYL-5-METHYL-2-THIOBIURETS

被引：27

作者：

CHO, NS ^{[1
]}

SHON, HI ^{[1
]}

PARKANYI, C ^{[1
]}

机构：

[1] FLORIDA ATLANTIC UNIV,DEPT CHEM,BOCA RATON,FL 33431

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1991年 / 28卷 / 07期

关键词：

D O I：

10.1002/jhet.5570280701

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

5-Aroylamino-2-methyl-2H-1,2,4,thiadiazol-3-ones 3 have been synthesized by oxidative cyclization of 1-aroyl-5-methyl-2-thiobiurets 2 with hydrogen peroxide in an alkaline solution. The needed 1-aroyl-5-methyl-2-thiobiurets 2 have been obtained through the addition of methylurea to the corresponding aroyl isothiocyanates.

引用

页码：1645 / 1649

页数：5

共 13 条

[1] C-13 SUBSTITUENT EFFECTS IN MONOSUBSTITUTED BENZENES
EWING, DF
[J]. ORGANIC MAGNETIC RESONANCE, 1979, 12 (09): : 499 - 524
[2] Ganapathi R. R., 1978, Patent No. [US 4093624, 4093624]
[3] CHEMISTRY OF 1,2,3,4-THIATRIAZOLES - SYNTHESIS OF 3-OXO-DELTA-4-1,2,4-THIADIAZOLIN-5-YL UREAS
KAUGARS, G
RIZZO, VL
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1979, 44 (22) : 3840 - 3843
[4] REACTION OF S-METHIODIDE DERIVATIVES OF ACTIVATED THIOUREAS WITH HYDROXYLIC COMPOUNDS - NOVEL SYNTHESIS OF MERCAPTANS
KLAYMAN, DL
SHINE, RJ
BOWER, JD
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1972, 37 (10) : 1532 - &
[5] THIADIAZOLES .6. 5-AMINO-3-HYDROXY-1-2-4-THIADIAZOLE DERIVATIVES
KURZER, F
TAYLOR, SA
[J]. JOURNAL OF THE CHEMICAL SOCIETY, 1958, (JAN): : 379 - 386
[6] THIADIAZOLES .12. ULTRAVIOLET ABSORPTION SPECTRA OF SOME 1,2,4-THIADIAZOLES
KURZER, F
TAYLOR, SA
[J]. JOURNAL OF THE CHEMICAL SOCIETY, 1962, (10): : 4191 - &
[7] KURZER F, 1956, CHEM IND-LONDON, P1482
[8] CYCLIC MESO-IONIC COMPOUNDS .23. NOVEL CHEMISTRY OF 1,2,4-THIADIAZOLES AND THEIR TRANSFORMATION INTO MESO-IONIC 1,2,4-THIADIAZOLIUM DERIVATIVES
NEWTON, CG
OLLIS, WD
WRIGHT, DE
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1984, (01): : 75 - 84
[9] CHEMISTRY OF N-HETEROCYCLIC SULFUR-COMPOUNDS - REACTION OF 2,5-DIMERCAPTO-1,3,4-THIADIAZOLES WITH 1,OMEGA-DIBROMOALKANES - SYNTHESIS OF TETRATHIA[(N + 2).(N + 2)](2,5)-1,3,4-THIADIAZOLOPHANES AND DITHIA[(N + 1).(N + 1)](3,5)-1,3,4-THIADIAZOLINOPHANEDITHIONES
PAPPALARDO, S
BOTTINO, F
TRINGALI, C
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1987, 52 (03) : 405 - 412
[10] 2-(2',3'-DIHYDROXYPROPYL)-5-AMINO-2H-1,2,4-THIADIAZOL-3-ONE AND 3-(2',3'-DIHYDROXYPROPYL)-5-AMINO-3H,1,3,4-THIADIAZOL-2-ONE
PARKANYI, C
YUAN, HL
CHO, NS
JAW, JHJ
WOODHOUSE, TE
AUNG, TL
[J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 1989, 26 (05) : 1331 - 1334

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