RAMAN-SPECTROSCOPIC STUDY OF THE EFFECTS OF OPIATES ON DIPALMITOYLPHOSPHATIDYLCHOLINE DISPERSIONS

被引：2

作者：

YOVA, D ^{[1
]}

ZOUBOULIS, I ^{[1
]}

LIAROKAPIS, E ^{[1
]}

LOUKAS, S ^{[1
]}

机构：

[1] HELLEN COMMISS ATOM ENERGY,INST BIOL,ATHENS,GREECE

来源：

JOURNAL OF RAMAN SPECTROSCOPY | 1990年 / 21卷 / 04期

关键词：

D O I：

10.1002/jrs.1250210407

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

The effects of the opiates levorphanol and naloxone on the thermotropic properties of dipalmitoylphospalidylcholine (DPPC) multilamellar dispersions were studied using Raman spectroscopy. The spectra of DPPC dispersions were recorded in the CH stretching mode region. By examining the intensity ratios I2880/I2850 and I2930/I2880 as a function of temperature, it was found that opiates lowered the pretransition temperature of DPPC by 2°C and decreased the lateral packing of the acyl chains of the phospholipids. Copyright © 1990 John Wiley & Sons, Ltd.

引用

页码：251 / 254

页数：4

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