ARYLAMIDATION OF QUANOSINE BY A CARCINOGEN, 2-AMINOFLUORENE - INTRAMOLECULAR APPROACH

被引：11

作者：

DEFRANCQ, E ^{[1
]}

LETERME, A ^{[1
]}

PELLOUX, N ^{[1
]}

LHOMME, MF ^{[1
]}

LHOMME, J ^{[1
]}

机构：

[1] UNIV J FOURIER,LAB ETUD DYNAM & STRUCT SELECTIV,CNRS,URA 332,BP 53X,F-38041 GRENOBLE,FRANCE

来源：

TETRAHEDRON | 1991年 / 47卷 / 30期

关键词：

D O I：

10.1016/S0040-4020(01)86525-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Model compound 3 in which the protected guanosine moiety is linked to the carcinogen (N-acetyl-N-hydroxy)-2-aminofluorene has been prepared and studied in various solvolytic conditions. The intramolecular reaction leads notably to the arylamidation of the guanine ring by the carcinogen.

引用

页码：5725 / 5736

页数：12

共 51 条

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