1-METHYL-4-(2'-METHYLPHENYL)-1,2,3,6-TETRAHYDROPYRIDINE(2'-CH3-MPTP) IS A MORE POTENT DOPAMINERGIC NEUROTOXIN THAN MPTP IN MICE

被引：60

作者：

YOUNGSTER, SK

DUVOISIN, RC

HESS, A

SONSALLA, PK

KINDT, MV

HEIKKILA, RE

机构：

[1] UNIV MED & DENT NEW JERSEY,RUTGERS MED SCH,DEPT NEUROL,PISCATAWAY,NJ 08854

[2] UNIV MED & DENT NEW JERSEY,RUTGERS MED SCH,DEPT ANAT,PISCATAWAY,NJ 08854

来源：

EUROPEAN JOURNAL OF PHARMACOLOGY | 1986年 / 122卷 / 02期

关键词：

D O I：

10.1016/0014-2999(86)90115-9

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：283 / 287

页数：5

共 9 条

[1] PERMANENT HUMAN PARKINSONISM DUE TO 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) - 7 CASES
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[2] A PRIMATE MODEL OF PARKINSONISM - SELECTIVE DESTRUCTION OF DOPAMINERGIC-NEURONS IN THE PARS COMPACTA OF THE SUBSTANTIA NIGRA BY N-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE
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[3] PARGYLINE AND DEPRENYL PREVENT THE NEUROTOXICITY OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) IN MONKEYS
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LEIST, A
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[J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 1984, 106 (01) : 209 - 210
[4] INFLUENCE OF SELECTIVE, REVERSIBLE INHIBITORS OF MONOAMINE-OXIDASE ON THE PROLONGED DEPLETION OF STRIATAL DOPAMINE BY 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE IN MICE
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[J]. LIFE SCIENCES, 1985, 37 (12) : 1089 - 1096
[5] NEUROCHEMICAL AND HISTOCHEMICAL CHARACTERIZATION OF NEUROTOXIC EFFECTS OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE ON BRAIN CATECHOLAMINE NEURONS IN THE MOUSE
HALLMAN, H
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OLSON, L
STROMBERG, I
JONSSON, G
[J]. JOURNAL OF NEUROCHEMISTRY, 1985, 44 (01) : 117 - 127
[6] DOPAMINERGIC NEUROTOXICITY OF 1-METHYL-4-PHENYL-1,2,5,6-TETRAHYDROPYRIDINE IN MICE
HEIKKILA, RE
HESS, A
DUVOISIN, RC
[J]. SCIENCE, 1984, 224 (4656) : 1451 - 1453
[7] STUDIES ON THE OXIDATION OF THE DOPAMINERGIC NEUROTOXIN 1-METHYL-4-PHENYL-1,2,5,6-TETRAHYDROPYRIDINE BY MONOAMINE OXIDASE-B
HEIKKILA, RE
MANZINO, L
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DUVOISIN, RC
[J]. JOURNAL OF NEUROCHEMISTRY, 1985, 45 (04) : 1049 - 1054
[8] HEIKKILA RE, 1984, NATURE, V311, P467, DOI 10.1038/311467a0
[9] PARKINSONISM-INDUCING NEUROTOXIN, N-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE - UPTAKE OF THE METABOLITE N-METHYL-4-PHENYLPYRIDINE BY DOPAMINE NEURONS EXPLAINS SELECTIVE TOXICITY
JAVITCH, JA
DAMATO, RJ
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SNYDER, SH
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (07) : 2173 - 2177

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