COMPARISON OF RECOVERY INDEX OF ROCURONIUM OR VECURONIUM WITH SIMULTANEOUSLY ADMINISTERED PANCURONIUM IN THE ISOLATED FOREARM

被引：5

作者：

FAWCETT, WJ ^{[1
]}

FAUVEL, NJ ^{[1
]}

FELDMAN, SA ^{[1
]}

机构：

[1] WESTMINSTER MED SCH & HOSP,MAGILL DEPT ANAESTHET,LONDON SW1P 2AP,ENGLAND

来源：

ANAESTHESIA | 1993年 / 48卷 / 03期

关键词：

NEUROMUSCULAR RELAXANTS; ROCURONIUM; VECURONIUM; PANCURONIUM;

D O I：

10.1111/j.1365-2044.1993.tb06900.x

中图分类号：

R614 [麻醉学];

学科分类号：

100217 [麻醉学];

摘要：

A series of isolated forearm experiments is described in which rocuronium or vecuronium were injected into one arm, and pancuronium injected simultaneously into the contralateral arm. The time for 25%–75% twitch recovery (recovery index) was recorded in both arms. The recovery indices of rocuronium and vecuronium were similar, but that of pancuronium significantly longer. Because the recovery indices compared in any one experiment occurred in the presence of identical background plasma concentration, the differences observed in recovery index between pancuronium and either rocuronium or vecuronium are due to different rates of dissociation from the effect compartment at the neuromuscular junction. Copyright © 1993, Wiley Blackwell. All rights reserved

引用

页码：200 / 201

页数：2

共 3 条

[1]

DOSE-RESPONSE RELATIONSHIP AND TIME COURSE OF ACTION OF ORG 9426 - A NEW MUSCLE-RELAXANT OF INTERMEDIATE DURATION EVALUATED UNDER VARIOUS ANESTHETIC TECHNIQUES [J].

LAMBALK, LM ;

DEWIT, APM ;

WIERDA, JMKH ;

HENNIS, PJ ;

AGOSTON, S .

ANAESTHESIA, 1991, 46 (11) :907-911

[2]

NAGASHIMA H, 1989, Anesthesiology (Hagerstown), V71, pA773, DOI 10.1097/00000542-198909001-00773

[3]

CLINICAL OBSERVATIONS ON THE NEUROMUSCULAR BLOCKING ACTION OF ORG-9426, A NEW STEROIDAL NONDEPOLARIZING AGENT [J].

WIERDA, JMKH ;

DEWIT, APM ;

KUIZENGA, K ;

AGOSTON, S .

BRITISH JOURNAL OF ANAESTHESIA, 1990, 64 (04) :521-523

← 1 →