A CATALYTIC ASYMMETRIC-SYNTHESIS OF ALPHA-METHYLENE LACTONES BY THE PALLADIUM-CATALYZED CARBONYLATION OF PROCHIRAL ALKENYL HALIDES

被引：57

作者：

SUZUKI, T ^{[1
]}

UOZUMI, Y ^{[1
]}

SHIBASAKI, M ^{[1
]}

机构：

[1] HOKKAIDO UNIV,FAC PHARMACEUT SCI,SAPPORO,HOKKAIDO 060,JAPAN

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1991年 / 22期

关键词：

D O I：

10.1039/c39910001593

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A catalytic asymmetric synthesis of the alpha-methylene lactones starting with the prochiral alkenyl halides 8 and 19 has been achieved for the first time, giving 9 in 57% enantiomeric excess (e.e.) and 20 in 39% e.e., respectively.

引用

页码：1593 / 1595

页数：3

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