NEUROLOGIC COMPLICATIONS OF PEDIATRIC LIVER-TRANSPLANTATION

被引：16

作者：

GARG, BP

WALSH, LE

PESCOVITZ, MD

PATEL, H

CHONG, S

FILO, RS

FITZGERALD, J

机构：

[1] INDIANA UNIV,MED CTR,DEPT NEUROL,PEDIAT NEUROL SECT,INDIANAPOLIS,IN

[2] INDIANA UNIV,MED CTR,DEPT SURG,TRANSPLANT SURG SECT,INDIANAPOLIS,IN

[3] INDIANA UNIV,MED CTR,DEPT MICROBIOL & IMMUNOL,INDIANAPOLIS,IN

[4] INDIANA UNIV,MED CTR,DEPT PEDIAT,INDIANAPOLIS,IN

来源：

PEDIATRIC NEUROLOGY | 1993年 / 9卷 / 06期

关键词：

D O I：

10.1016/0887-8994(93)90023-6

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The neurologic complications of 24 children, ages 5 months to 18 years, following orthotopic liver transplantation at the Indiana University hospitals are reported. Biliary atresia (14 patients) was the most common cause for orthotopic liver transplantation. Three children died. Seventeen children (70%) had no neurologic deficit on follow-up 6 months or longer after transplantation. Eleven children (46%), including 4 of 16 patients (25%) who had received OKT3, had neurologic complications. Seven children (29%) had new-onset seizures; 4 of these patients had status epilepticus. Two children had intracranial hemorrhage. Seizures occurred later in children than in adults following orthotopic liver transplantation and were not associated with poor prognosis. Longer term follow-up is indicated to assess subtle, cognitive deficits following liver transplantation in children.

引用

页码：444 / 448

页数：5

共 27 条

[11] CEREBROVASCULAR COMPLICATIONS AFTER ORTHOTOPIC LIVER-TRANSPLANTATION - A CLINICOPATHOLOGICAL STUDY [J].